Carbetocin

Chemical Name:Carbetocin

CAS:37025-55-1

Synonyms:Deamino-1-monocarba-2-O-methyltyrosine-oxytocin, Longastatin

Molecular Formula :C₄₅H₆₉N₁₁O₁₂S

Molecular Weight:Approximately 988.17 g/mol

Structure :Synthetic analogue of oxytocin with a modified structure for enhanced stability.

Appearance:White to off-white powder

Solubility：Soluble in water, slightly soluble in ethanol

Stability:Stable under recommended storage conditions (2-8°C, protected from light).

Biological Activity:Acts as an oxytocin receptor agonist; induces uterine contractions and prevents postpartum hemorrhage.

Pharmacological Use:- Prevention of postpartum hemorrhage after cesarean section or vaginal delivery.

- Management of uterine atony.

Storage:Store at 2-8°C (36-46°F) in a tightly sealed container, protected from light.

Safety:- Handle with care, avoiding inhalation or direct contact with skin/eyes.

- Use under medical supervision; potential side effects include nausea, vomiting, and hypotension.

Regulatory Status Approved for medical use in multiple countries, including Canada and the EU.

Carbetocin is a synthetic analogue of oxytocin designed for enhanced stability and prolonged activity. It is primarily used to prevent postpartum hemorrhage by inducing uterine contractions. Its chemical structure includes modifications that improve its resistance to enzymatic degradation, making it effective for clinical use. Proper storage and handling are essential to maintain its efficacy and safety.