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ChemicalBook Product Catalog BzATP triethylammonium salt

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BzATP triethylammonium salt NEW

$41.00 1mg

$97.00 5mg

$155.00 10mg

Min. Order
Purity96.26%
Cas No112898-15-4
Supply Ability10g
Update time2024-11-19

TargetMol Chemicals Inc.

TargetMol Chemicals Inc.

3YR

United States

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Chemical Properties

Product Name	BzATP triethylammonium salt
CAS No	112898-15-4
EC-No
Min. Order
Purity	96.26%
Supply Ability	10g
Release date	2024/11/19

Product Introduction

Bioactivity

Name	BzATP triethylammonium salt
Description	BzATP triethylammonium salt is a P2X7 receptor agonist.
In vitro	METHODS: Glioma cell lines U87 and U251 were treated with BzATP triethylammonium salt (5-1000 µM) for 2-72 h. Cell proliferation was detected by MTT assay. RESULTS: Proliferation of glioma cell lines U87 and U251 was significantly increased in the presence of BzATP. the peak fine cell proliferation of both U87 and U251 cell lines was 100 µM BzATP, and the optimal incubation time was 24 h for both cell lines [1]. METHODS: Retinal ganglion cells were treated with BzATP triethylammonium salt (50 µM) for 2 min and intracellular Ca2+ levels were measured. RESULTS: The P2X7 agonist BzATP resulted in a rapid increase in intracellular Ca2+ and the level remained elevated for 2 min after agonist application. More than 80% of the examined cells responded strongly to BzATP. [2]
In vivo	METHODS: To investigate the effects on whole-body energy metabolism, BzATP triethylammonium salt (1 mg/kg) was administered intraperitoneally to C57BL/6J mice once daily for seven days. RESULTS: BzATP triethylammonium salt increased metabolic rate and O2 consumption while decreasing respiratory rate and upregulating NADPH oxidase 2 in gastrocnemius and tibialis anterior muscle.The findings suggest that activation of P2X7 has a significant effect on energy homeostasis and muscle metabolism. [3]
Storage	store at low temperature,keep away from moisture,store under nitrogen \| Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice.
Solubility Information	H2O : 50 mg/mL (49.06 mM), Sonification is recommended. DMSO : 50 mg/mL (49.06 mM), Sonification is recommended.
Keywords	BzATP triethylammonium \| BzATP triethylammonium salt
Inhibitors Related	Aurintricarboxylic acid \| (E/Z)-Sivopixant \| PSB-12062 \| ATP disodium salt \| Oxatomide \| JNJ-42253432 \| Ivermectin \| Lappaconitine \| CTP disodium dihydrate \| Brilliant blue G-250
Related Compound Libraries	Bioactive Compound Library \| Membrane Protein-targeted Compound Library \| Peptide Compound Library \| NO PAINS Compound Library \| Bioactive Compounds Library Max \| Nucleotide Compound Library

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