Chemical Name: Brefeldin A
CAS No: 20350-15-6
Molecular Formula: C16H24O4
Molecular Weight: 280.36
Chemical Structure:
Appearance: A white crystalline powder
Assay: 98%
Brefeldin A Typical Properties
| Item | Specifications |
| Appearance | A white crystalline powder |
| Solubility | Soluble in methanol, chloroform |
| Water | ≤3% |
| Heavy Metals | <20ppm |
| Total Impurities(HPLC) | ≤2% |
| Purity(HPLC) | ≥98% |
Brefeldin A Usage
1. Brefeldin A, a commonly used protein transport inhibitor,
specifically reversibly blocks the transport of proteins from the
endoplasmic reticulum (ER) to the Golgi.
2. After Brefeldin A treatment, the Golgi apparatus is quickly
destroyed and fused to the endoplasmic reticulum, which exhibits energy,
temperature and microtubule dependence.
3. In mammals and yeast, Brefeldin A inhibition of protein transport
from the endoplasmic reticulum to the Golgi apparatus may be achieved by
a class of GTP-exchange factors that activate Afr1p GTPase.
4. Arf1p forms transport vesicles by recruiting coat proteins to the inner membrane of the cell.
Brefeldin APackaging and Shipping
Packing: Bottle
Delivery: Express or air
Brefeldin AStorage
A cool, ventilated, dry place.
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