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ChemicalBook Product Catalog BPTU

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BPTU NEW

$32.00 1mg

$45.00 2mg

$66.00 5mg

Min. Order
Purity99.89%
Cas No870544-59-5
Supply Ability10g
Update time2024-11-19

TargetMol Chemicals Inc.

TargetMol Chemicals Inc.

5YR

United States

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Chemical Properties

Product Name	BPTU
CAS No	870544-59-5
EC-No
Min. Order
Purity	99.89%
Supply Ability	10g
Release date	2024/11/19

Product Introduction

Bioactivity

Name	BPTU
Description	BPTU (BMS-646786) is an allosteric antagonist of P2Y1 (EC50 = 0.06-0.3 μM). Non-nucleotide ligand. Binds receptor outside of the helical bundle. Blocks inhibition of spontaneous contraction of rat and mouse colon induced by electrical field stimulation, nicotine and P2Y agonists. Antithrombotic; reduces platelet aggregation.
In vivo	Octreotide-treated groups show a significant reduction in the tumor volume when compared with saline group. Octreotide-PPSG (1.4 mg/kg, i.p.) shows greater antitumor effect than Octreotide-soln (100 μg/kg, i.p.). Octreotide-treatments results in significant inhibitory effect on the expression levels of SSTR2 and SSTR5 in primary HCC-bearing rats compared with the saline group. Octreotide-PPSG appears to inhibit the expression of SSTR2 and SSTR5 to a greater extent than that of Octreotide-soln treated group. A test dose of octreotide acetate significantly decreases the serum gastrin level to approximately one third of the baseline in 2 hr and the effect lasted approximately for 6 hr. On day 21, treatment with sustained-release formulation of octreotide acetatea (5 mg intramuscular, q 4 wk) is initiated.
Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice.
Solubility Information	DMSO : 20 mg/mL (44.9 mM), Sonication is recommended.
Keywords	antithrombotic \| BPTU \| thrombosis \| BMS646786 \| P2Y Receptor \| inhibit \| BMS 646786 \| Inhibitor
Inhibitors Related	Clopidogrel \| Prasugrel Hydrochloride \| Prasugrel \| PSB-16133 sodium \| Uridine 5′-diphosphoglucose disodium salt \| Regrelor disodium \| (±) Clopidogrel hydrogen sulfate \| Clopidogrel hydrogen sulfate \| Uridine-5'-diphosphate disodium salt \| N6-(4-Hydroxybenzyl)adenosine \| Diquafosol tetrasodium \| cangrelor tetrasodium
Related Compound Libraries	Target-Focused Phenotypic Screening Library \| Bioactive Compound Library \| Neuronal Signaling Compound Library \| Membrane Protein-targeted Compound Library \| Inhibitor Library \| NO PAINS Compound Library \| Bioactive Compounds Library Max \| Covalent Inhibitor Library \| GPCR Compound Library \| Anti-Cancer Compound Library

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Company Profile Introduction

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