Boc-L-Ala-OSu (tert-Butoxycarbonyl-L-Alanine-N-Hydroxysuccinimide Ester) is a commonly used amino acid derivative that finds widespread applications in biochemistry, drug design, and organic synthesis. Here are some of the primary applications of Boc-L-Ala-OSu:
Peptide Synthesis: Boc-L-Ala-OSu, as a protected derivative of amino acids, is frequently employed in solid-phase peptide synthesis (SPPS). Its reaction with amine groups allows the construction of polypeptide chains. In this process, the Boc group (tert-butoxycarbonyl) serves as a protective group for the amino group, maintaining its stability during synthesis, while the OSu group (N-hydroxysuccinimide ester) facilitates the reaction with the amino group of another amino acid or peptide segment.
Protein Modification: Due to its reactive nature, Boc-L-Ala-OSu can also be used for site-specific modification of proteins. This modification can alter the properties, activity, or stability of proteins, enabling further studies on protein function or the development of novel drugs. Drug Design and Development: In drug chemistry, amino acid derivatives like Boc-L-Ala-OSu serve as building blocks for the synthesis of small-molecule compounds with specific biological activities. By binding these compounds to target molecules, new therapeutic strategies or drugs can be developed. | 
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