Name | Bismuth Subsalicylate |
Description | Bismuth Subsalicylate (Bismuth subsalicylat) is the active ingredient in the popular medication Pepto-Bismol that is used to treat nausea, heartburn, indigestion, upset stomach, diarrhea, and other temporary discomforts of the stomach and gastrointestinal tract. |
In vivo | Bismuth Subsalicylate is metabolized in the gastrointestinal tract into salicylic acid and insoluble bismuth salts. It inhibits Prostaglandin G/H Synthase 1/2 (cyclooxygenase-1/2, COX-1/2), thereby reducing inflammation and irritation of the gastric and intestinal mucosa. |
Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO : 27.5 mg/mL (75.95 mM), Sonication is recommended. H2O : Insoluble
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Keywords | sick | Prostaglandin E synthase | PGESynthase | PGE synthase | PGE Synthase | nausea,?salicylate | Inhibitor | inhibit | inflammation | heartburn | COX-2 | COX-1 | Bismuth Subsalicylate | antacid | acid reflux,?indigestion,?diarrhoea |
Inhibitors Related | Phenacetin | Ibuprofen | Acetaminophen | Salicylamide | Diclofenac sodium | Diclofenac Potassium | Paradol | Indomethacin sodium hydrate | Salicylic acid | Glafenine | Trometamol | Revaprazan hydrochloride |
Related Compound Libraries | Failed Clinical Trials Compound Library | Pain-Related Compound Library | Bioactive Compound Library | ReFRAME Related Library | Anti-Cancer Clinical Compound Library | Drug Repurposing Compound Library | FDA-Approved Drug Library | Anti-Cancer Approved Drug Library | Immunology/Inflammation Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Anti-Cancer Drug Library |