| Name | beta-Amyrin acetate |
| Description | beta-Amyrin acetate inhibits HMG-CoA Reductase (HMGCR) and sEH activity with IC50 of 3.4 μM. beta-Amyrin acetate has anti-inflammatory, antifungal, antioxidant, and anti-hyperlipidemic activities. |
| In vitro | beta-Amyrin acetate (25 μM) decreases mEH activity to 61% of control activity[1]. beta-Amyrin acetate (50 μg/mL) inhibits heat-induced hemolysis and hypotonicity-induced hemolysis of human erythrocytes[2]. beta-Amyrin acetate (7.8-1000 μg/mL) inhibits all of the Candida fungal species tested (MIC: 30 - 250 μg/mL)[5]. |
| In vivo | In Xylene-induced mouse ear topical edema model, beta-Amyrin acetate (100 μg/ear) significantly inhibits xylene-induced ear edema[2]. In normal and arthritic rats, beta-Amyrin acetate (40 mg/kg; s.c.) increases the ATP-phosphohydrolase activity in liver homogenates. In adult albino rats, beta-Amyrin acetate (40 mg/kg; i.p.) shows significant anti-inflammatory activities to 43.6% with mean average weight of granulation tissue of 9.2 mg after 6 days[4]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : Insoluble
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| Keywords | HMG-CoA | betaAmyrin acetate | LDL | Fungal | beta-Amyrin Acetate | inhibit | Inhibitor | arthritic | hemolysis | antifungal | b-Amyrin Acetate | anti-inflammatory | HMG-CoA Reductase (HMGCR) | inflammation | β-Amyrin | beta Amyrin acetate | β-Amyrin Acetate |
| Inhibitors Related | Dehydroacetic acid sodium | Chlorobutanol hemihydrate | 2-Butyl-1,2-benzisothiazolin-3-one | Potassium gluconate | Chitosan (MW 150000) | Methyl 2-amino-5-bromobenzoate | Veratraldehyde | Paclobutrazol | Lauryl betaine | Propyl gallate | Geraniol | L-Cystine |
| Related Compound Libraries | Terpene Natural Product Library | Traditional Chinese Medicine Monomer Library | Bioactive Compound Library | Anti-Fungal Compound Library | Miao medicine Compound Library | Anti-Inflammatory Traditional Chinese Medicine Compound Library | Natural Product Library for HTS | Anti-infective Natural Product Library | Bioactive Compounds Library Max |
United States
