| Name | beta-Amyrin acetate |
| Description | beta-Amyrin acetate inhibits HMG-CoA Reductase (HMGCR) and sEH activity with IC50 of 3.4 μM. beta-Amyrin acetate has anti-inflammatory, antifungal, antioxidant, and anti-hyperlipidemic activities. |
| In vitro | beta-Amyrin acetate (25 μM) decreases mEH activity to 61% of control activity[1]. beta-Amyrin acetate (50 μg/mL) inhibits heat-induced hemolysis and hypotonicity-induced hemolysis of human erythrocytes[2]. beta-Amyrin acetate (7.8-1000 μg/mL) inhibits all of the Candida fungal species tested (MIC: 30 - 250 μg/mL)[5]. |
| In vivo | In Xylene-induced mouse ear topical edema model, beta-Amyrin acetate (100 μg/ear) significantly inhibits xylene-induced ear edema[2]. In normal and arthritic rats, beta-Amyrin acetate (40 mg/kg; s.c.) increases the ATP-phosphohydrolase activity in liver homogenates. In adult albino rats, beta-Amyrin acetate (40 mg/kg; i.p.) shows significant anti-inflammatory activities to 43.6% with mean average weight of granulation tissue of 9.2 mg after 6 days[4]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | H2O : < 1 mg/mL (insoluble)
DMSO : < 1 mg/mL (insoluble)
Ethanol : < 1 mg/mL (insoluble)
|
| Keywords | β-Amyrin Acetate | β-Amyrin | sEH | LDL | Inhibitor | inhibit | inflammation | Immunology & Inflammation related | HMGCoAReductase | HMG-CoA Reductase (HMGCR) | HMGCoA Reductase | HMG-CoA | hemolysis | Fungal | EpoxideHydrolase | Epoxide Hydrolase | beta-Amyrin Acetate | betaAmyrin acetate | beta Amyrin acetate | b-Amyrin Acetate | arthritic | Antioxidant | anti-inflammatory | antifungal | Antifungal |
| Inhibitors Related | Dehydroacetic acid sodium | Potassium gluconate | 5-Hydroxymethylfurfural | Methyl 2-amino-5-bromobenzoate | Terbinafine hydrochloride | AFMK | Lauryl betaine | Geraniol | Luliconazole | L-Cystine | L-Citronellol | 6-PPD |
| Related Compound Libraries | Terpene Natural Product Library | Traditional Chinese Medicine Monomer Library | Selected Plant-Sourced Compound Library | Anti-Inflammatory Traditional Chinese Medicine Compound Library | Miao medicine Compound Library | Natural Product Library | Natural Product Library for HTS | Anti-Aging Compound Library | Bioactive Compounds Library Max | Heat-Clearing and Detoxifying Traditional Chinese Medicine Compound Library | Ancient Chinese Classical Formulas Compound Library | Food as Medicine Compound Library |
United States
