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ARA-290
Size: 16mg
Contents: ARA-290 (16mg)
Form: Lyophilized powder
Purity: >99%
SKU: P-ARA290-16
ARA-290 Peptide
ARA-290 peptide is a 11 amino acid chain derived from the beta domain of protein erythropoietin, a part of the erythropoietin (EPO) considered to assist in tissue regeneration and repair (1). Scientists consider the primary function of the EPO is to stimulate body tissues to produce red blood cells. While the mechanism is not fully understood, EPO is considered by scientists to regulate and optimize the oxygen levels in the body – when the levels are low, more EPO is produced; when the levels are optimal, lesser EPO is produced.
Researchers isolated a small peptide molecule from the EPO protein, called cibinetide, better known as the ARA-290 peptide. Researchers are pivoting their study theses to expand the potential applications of ARA-290 in their research, as the peptide has exhibited versatile potential beyond possible oxygenation and blood cell maintenance.
Overview
Scientific findings (4) thus far indicate that once the tissue undergoes an injury, a tissue protective receptor (TPR) pathway is activated. This TPR receptor mainly consists of a beta receptor unit (CD131) along with a subunit from the EPO receptor, jointly called the innate repair receptor. The ARA-290 peptide molecule has been suggested by researchers to bind to this innate repair receptor and possibly attenuate nerve and allodynia-led pain (2). It is also suggested that the ARA-290 peptide may act primarily via this IRR mediated pathway.
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