| Name | Anhydrotetracycline hydrochloride |
| Description | Anhydrotetracycline (hydrochloride) is a potent competitive inhibitor of broad-spectrum tetracycline destructase enzymes. |
| In vitro | Anhydrotetracycline (hydrochloride), a tetracycline biosynthetic precursor, inhibited Tet50, TetX, TetX-3 degradations of tetracyclines with the IC50s of 210 μM, 41 μM and 3 μM,respectively. Anhydrotetracycline (hydrochloride) inhibited Tet50, TetX, TetX-3 degradations of demeclocycline with the IC50s of 120 μM, 41 μM, 7 μM,respectively. Anhydrotetracycline (hydrochloride) inhibited Tet50, TetX, TetX-3 degradations of chlortetracycline with the IC50s of 210 μM, 75 μM, 26 μM,respectively[1]. |
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 125 mg/mL (270.05 mM), Sonication is recommended.
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| Keywords | tetracycline | Tet50 | Inhibitor | inhibit | eukaryotic | enzymes | destructase | demeclocycline | chlortetracycline | biosynthetic | Bacterial | Antibiotic | Antibacterial | Anhydrotetracycline Hydrochloride | Anhydrotetracycline hydrochloride | Anhydrotetracycline |
| Inhibitors Related | Neomycin sulfate | Dehydroacetic acid sodium | Ampicillin sodium | Methyl anthranilate | Kanamycin sulfate | Urethane | Sulfamethoxazole sodium | Terbinafine hydrochloride | Doxycycline | Penicillin G potassium | Dimethyl sulfoxide | Ethyl acetoacetate |
| Related Compound Libraries | Bioactive Compound Library | Antibiotics Library | Inhibitor Library | Anti-Bacterial Compound Library | Bioactive Compounds Library Max | Covalent Inhibitor Library | Anti-Infection Compound Library |