Product Name: Andrographolide
CAS No.: 5508-58-7
Molecular Formula: C20H30O5
Molecular Weight: 350.45
Synonyms: 3-[2-(3,4-dihydroxy-5-methoxyphenyl)-2-oxoethyl]-14-deoxyandrographolide
EINECS No.: 226-969-8
1. Product Description
Andrographolide is a diterpene lactone extracted from Andrographis paniculata. It is widely recognized for its anti-inflammatory, antioxidant, hepatoprotective, and immune-modulating properties, suitable for nutraceuticals, pharmaceuticals, cosmetics, and industrial applications.
2. Physical & Chemical Properties
| Item | Specification |
|---|
| Appearance | White to off-white crystalline powder |
| Odor & Taste | Characteristic, bitter |
| Purity (HPLC) | ≥ 98.0% |
| Melting Point | 230 – 235 °C |
| Solubility | Soluble in ethanol and methanol; practically insoluble in water |
| Stability | Stable under normal storage; sensitive to light and heat |
| Loss on Drying | ≤ 0.5% |
| Residue on Ignition (Ash) | ≤ 0.5% |
3. Quality Standards
Heavy Metals: ≤ 10 ppm
Lead (Pb): ≤ 3 ppm
Arsenic (As): ≤ 2 ppm
Cadmium (Cd): ≤ 1 ppm
Mercury (Hg): ≤ 0.1 ppm
Microbiological Test (Food Grade):
Total Plate Count: ≤ 1,000 CFU/g
Yeast & Mold: ≤ 100 CFU/g
E. coli: Negative
Salmonella: Negative
Staphylococcus aureus: Negative
4. Applications
Food & Nutraceuticals (Food Grade):
Ingredient in dietary supplements, capsules, tablets, powders.
Functional additive for immune support, liver protection, and anti-inflammatory effects.
Antioxidant component in health drinks and fortified foods.
Pharmaceutical & Cosmetics:
Raw material for anti-inflammatory and hepatoprotective drugs.
Used in cosmetic products for antioxidant and skin protection.
Industrial Grade Applications:
Intermediate for pharmaceutical synthesis.
Applied in biochemical research and functional material development.
Formulation of plant-based active compounds for industrial biotech.
5. Packaging
Food Grade: 1 kg aluminum foil bags, 25 kg fiber drums
Industrial Grade: 25 kg fiber drums or customized packaging
6. Storage & Shelf Life
Store in a cool, dry, well-ventilated place, away from sunlight, heat, and moisture
Keep container tightly closed
Shelf life: 24 months under proper storage conditions
7. Safety & Handling
Non-toxic at recommended usage levels
Avoid inhalation of dust; use protective equipment as needed
Handle according to Good Manufacturing Practices (GMP)
Refer to MSDS for detailed safety instructions
If you need other products, please click the website below to make a selection
.http://www.khonorchem.com
China
