Name | Amylin, amide, rat acetate(124447-81-0,free base) |
Description | Amylin, amide, rat acetate is a potent and high affinity ligand of AMY1 and AMY3 receptors and variably of AMY2 receptors. |
In vivo | Amylin is an important 37 amino acid glucoregulatory hormone with great potential to target metabolic diseases. Amylin is a member of the calcitonin (CT) family of peptides, which includes CT itself, the CGRPs comprising two variants (αCGRP and βCGRP), adrenomedullin (AM) and AM2 (intermedin). Amylin is a centrally acting, neuroendocrine hormone synthesized with insulin in the beta cells of pancreatic islets. Amylin regulates glucose homeostasis by inhibiting gastric emptying, inhibiting the release of the counter-regulatory hormone glucagon and inducing meal-ending satiety. Amylin functions as a glucoregulatory and satiety-inducing hormone, which is protective against postprandial spikes in blood glucose and overeating.[1] |
Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Keywords | Amylin, amide, rat acetate(124447810,free base) | Amylin, amide, rat acetate(124447 81 0,free base) | Amylin, amide, rat acetate(124447-81-0,free base) |
Inhibitors Related | AC 187 Acetate | cAC 253 acetate |
Related Compound Libraries | Peptide Compound Library | NO PAINS Compound Library |