Pharmacological action
Antiparasitic drugs. Albendazole has wide
It has strong repellent activity against nematode, green worm and fluke
Yes. Its mechanism of action is by binding with the microtubulin in the worm, preventing it from polymerizing with A-tubulin to form microtubules
It also affects the cell reproduction processes such as mitosis, protein assembly and energy metabolism.
Ivermectin has a good repellant effect on internal and external parasites, especially arthropods and nematodes, and is mainly used to expel cattle, sheep and so on
Gastrointestinal nematodes, lungworms and ectoparasites of animals. Its repellent mechanism is to promote the release of gamma-aminobutyric acid from presynaptic neurons
(GABA), thus opening GABA-mediated chloride ion channels. Chloride ion flow can reduce the membrane impedance and cause postsynaptic membrane stasis
The potential is slightly depolarized, which interferes with the signal transmission between neuromuscles, relaxes and paralyzes the worm, resulting in death or expulsion of the worm
Outside the body.
China
