Agomelatine CAS 138112-76-2
Agomelatine is a competitive antagonist of human and porcine serotonin (5-HT2C) receptors (pKi = 6.2 and 6.4, respectively) as well as human 5-HT2B receptors (pKi = 6.6). IC50 value: 6.2 (pKi, 5-HT2c); 6.6 (pKi, 5-HT2b)Target: 5-HT2C Receptor; 5-HT2B receptorIt is classified as a norepinephrine-dopamine disinhibitor (NDDI) due to its antagonism of the 5-HT2C receptor. Activation of 5-HT2C receptors by serotonin inhibits dopamine and norepinephrine release. Antagonism of 5-HT2C results in an enhancement of DA and NE release and activity of frontocortical dopaminergic and adrenergic pathways. Agomelatine is also a potent agonist at melatonin receptors which makes it the first melatonergic antidepressant. Agomelatine is an antidepressant drug.
| Common Name | Agomelatine |
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| CAS Number | 138112-76-2 | Molecular Weight | 243.301 |
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| Density | 1.1±0.1 g/cm3 | Boiling Point | 478.8±28.0 °C at 760 mmHg |
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| Molecular Formula | C15H17NO2 | Melting Point | 107-109ºC |
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| MSDS | ChineseUSA | Flash Point | 243.4±24.0 °C |
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Company Introduction
Hebei Best Biological Technology Co., Ltd. is a modern advanced enterprise specializing in production and exportation of APIs,Pharmaceutical intermediates, peptides, plant extracts etc. Our products are widely used in medicine, health care products,cosmetics, nutritional supplements and food additives areas.
our factory covers an area of 95 acres, the proposed construction of the plant will be GMP standards, the factory environment clean and tidy, rational layout, with large and medium-sized production workshop and reprocessed shop. It is equipped with advanced equipment quality inspection and research center. Those products of both quality and technical content have reached the domestic advanced level.
Since its establishment, the company has attached great importance to the team training and technical reform. Our modern production equipment guarantees for a fast and effective production with a superior degree of accuracy throughout the whole production line, everything is done in-house, processing,
extraction, packaging and transportation of all links, ensuring maximum quality and efficiency. We are constantly research and development new ingredients and innovative new products, have earned the respect & admiration from the worldwide customers.
After years of continuous development, the company has accumulated rich experience in international trade and customer resources, established a stable customer base and perfect marketing service network. In addition, the company has established long-term technical cooperation with experts and professors from many universities and research institutes in the province. Excellent quality, reasonable price, rapid delivery and good service ensure us to satisfy all kinds of your demands.
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Why Choose Us
1. Rich experience
We specialize in this filed for many years, our steriods and hormones exported to all over the world and established long friendly relations of cooperation with them.
2. Great quality,purity and favorable
Good quality is one of our biggest secret to success; you can get the best quality and service from us.
3. Safest and fastest delivery
We have adequate stock so that we can deliver the products with 24 hours as soon as receiving the payment. Fast and discreet shipment will be arranged to pass customs.
4. Good package
Unique ways to ship 10g to 100kg powders to your destination. We offer melting powder into liquid service and ship the liquid in special bottles.
5. Great after-sales service
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FAQ
Q1: What is your MOQ?
A:Our MOQ is 10g, 100g and 1kg for your evaluation quality of our goods on the condition that sample charge is 100% paid.
Q2: Is there any discount?
A:Yes, for larger quantity, we always support with better price.
Q3: What payment terms do you accept ?
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Q4: How long will it take to get the goods?
A:Depending on your location, For small order, please expect 5-7 days by DHL, UPS, TNT, FEDEX, EMS. For mass order, please allow 5-8 days by Air, 20-35 days by Sea.
Q5: How do you treat quality complaint?
A: First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
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A: You are always warmly welcomed to visit us at any time. Before we start B2B, MIC has audited our company on-spot and approved our credit.
Q7: Do you test all your goods before delivery?
A: Yes, we have 100% test before delivery,International Authorized Third-Party Test for the products if you need are highly welcomed.
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