| Name | Adenosine 5'-diphosphate |
| Description | Adenosine 5'-diphosphate (ADP) is a naturally occurring nucleotide derived from the dephosphorylation of ATP. Adenosine 5'-diphosphate is essential for cellular metabolism and induces platelet aggregation. |
| In vitro | METHODS: Fibroblast-like synoviocytes FLS1 were treated with Adenosine 5'-diphosphate (100 µM) for 24 h, and gene expression levels were measured by RT-qPCR.
RESULTS: MCP-1/CCL-2 mRNA expression was up-regulated 2.31-fold in FLS1 cells treated with Adenosine 5'-diphosphate (100 µM). [1] |
| In vivo | METHODS: To investigate the role in tissue repair, Adenosine 5'-diphosphate (15.2 µg/kg) was applied topically to diabetic mice in a total excisional wound model once daily for 14 days.
RESULTS: Adenosine 5'-diphosphate accelerated cutaneous wound healing, improved new tissue formation, and increased collagen deposition and TGF-β production in the wounds.Adenosine 5'-diphosphate acts as a pro-absorptive mediator in diabetes-related cutaneous wounds. [2] |
| Storage | store at low temperature,store under nitrogen,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | H2O : 100 mg/mL (234.08 mM), Sonication is recommended.
DMSO : 14 mM, Sonication is recommended.
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| Keywords | Inhibitor | inhibit | EndogenousMetabolite | Endogenous Metabolite | adenosine Pyrophosphate | Adenosine Diphosphate | Adenosine 5'-diphosphate | Adenosine 5'diphosphate | Adenosine 5' diphosphate | Adenosine |
| Inhibitors Related | Sucrose | Acetaminophen | Daidzein | Guanidine hydrochloride | Fumaric acid | Ferulic Acid | L-Methionine | Formamide | Glycerol | Thymidine | Naringin | 3-Indoleacetic acid |
| Related Compound Libraries | Anti-Tumor Natural Product Library | Bioactive Compound Library | Natural Product Library | Anti-Viral Compound Library | Tobacco Monomer Library | Natural Product Library for HTS | Human Endogenous Metabolite Library | Anti-infective Natural Product Library | Bioactive Compounds Library Max | Gut Microbial Metabolite Library | Preclinical Compound Library | Anti-Cancer Active Compound Library |
United States
