Ivabradine hydrochloride

$ 1.00 /1kg

Min. Order1kg
Purity99%
Cas No148849-67-6
Supply Ability1
Update time2025-10-13

Wuhan Haorong Biotechnology Co.,ltd

VIP3Y

China

Since:2019-11-21

Address:Room E020, 4th Floor (1-3), Building 5, International Enterprise Center, No.1 Guanshan Second Road,

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Chemical Properties

Product Name	Ivabradine hydrochloride
CAS No	148849-67-6
EC-No
Min. Order	1kg
Purity	99%
Supply Ability	1
Release date	2025/10/13

Pharmaceutical Grade Ivabradine Hydrochloride CAS:148849-67-6 GMP Certified Supplier

Chemical Name：Ivabradine hydrochloride

CAS:148849-67-6

IUPAC Name:3-{[(7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl}-methylaminoethyl ester of (3R)-1,3,4,5-tetrahydro-7,8-dimethoxy-3-[3-([(1S)-1,4,6,7-tetrahydro-4-methyl-5H-indazol-5-yl]propyl)-1H-3-benzazepin-2-one hydrochloride

Molecular Formula:C27H36N2O5·HCl

Molecular Weight:505.05 g/mol

Appearance:White or almost white crystalline powder

Solubility:Freely soluble in water, methanol, and ethanol; slightly soluble in acetone

Melting Point:~195–197 °C (with decomposition)

pKa:~9.4 (basic)

Partition Coefficient (LogP):~2.7 (lipophilic)

Pharmacological Class:Selective If (funny current) channel inhibitor

Mechanism of Action:Reduces heart rate by inhibiting the pacemaker current (If) in the sinoatrial node without affecting myocardial contractility or conduction

Therapeutic Uses:Treatment of chronic heart failure (HFrEF) and stable angina pectoris in patients with elevated heart rate

Protein Binding:~70%

Excretion Primarily via feces (≈70%) and urine (≈20%)

Brief Introduction

Ivabradine hydrochloride is a selective sinus node inhibitor that specifically blocks the If current in cardiac pacemaker cells, reducing heart rate without negative inotropic effects. It is clinically used to manage chronic heart failure (especially HFrEF) and stable angina in patients with elevated resting heart rates who are intolerant to beta-blockers.

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Company Profile Introduction

Wuhan Hao Rong Biotechnology Co., Ltd., located in East Lake high tech Development Zone, Wuhan, is a company specializing in the production and operation of chemical raw materials, flavors and fragrances, food additives, agrochemicals and other products. The company has first-class production equipment, advanced production technology, scientific management system, perfect detection means, and an excellent R & D team. The R & D center of the company has a technical team specialized in research and development, as well as a number of advanced detection, experiment and pilot equipment, and has established a good technical support relationship with a number of scientific research institutions, with strong technical force. The company has a wide range of products, in line with the quality of survival, service and development, customer-centric, integrity management philosophy, do our best to provide customers with quality and cheap raw materials. In addition, haorong also helps customers develop and implement customized system solutions. In these core areas of the chemical industry, haorong's core expertise covers chemicals and application technology, flexible asset management and customized services.