1. Product information
Names
| Name | all-cis-docosa-7,10,13,16-tetraenoic acid |
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| Synonym | More Synonyms |
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Adrenic Acid Biological Activity
| Description | Adrenic Acid is an inflammation enhancer in non-alcoholic fatty liver disease. |
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| Related Catalog | Research Areas >> Inflammation/Immunology Research Areas >> Metabolic Disease Natural Products >> Others |
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| Target | Human Endogenous Metabolite |
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| In Vitro | Adrenic acid is produced via the elongation of arachidonic acid by ELOVL2 and 5. Interestingly, the hepatic level of free Adrenic Acid (22:4n6) is markedly higher in the CDAHFD-fed db/db mice than in the SD-fed db/db mice. In plasma, the difference in the adrenic acid level reaches statistical significance (p<0.001). It is also found that the concentrations of phospholipid species containing Adrenic Acid, such as PC or PE (40:4) (containing side chain 18:0/22:4), and LPC 22:4 (sn-1/sn-2), are also significantly increased. (sn-1/sn-2). The hepatic and plasma levels of Adrenic Acid, which is an omega 6 polyunsaturated fatty acid (PUFA), exhibit greater differences between the CDAHFD-fed db/db mice and the SD-fed db/db mice (8.6-fold higher vs. 1.6-fold higher in liver tissue, 5.3-fold higher vs. 2.2-fold higher in plasma) than those of well-known proinflammatory PUFA, such as Arachidonic Acid[1]. |
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| References | [1]. SautHoras H Nababan, et al. Adrenic acid as an inflammation enhancer in non-alcoholic fatty liver disease. Arch Biochem Biophys. 2017 Jun 1;623-624:64-75. |
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Chemical & Physical Properties
| Density | 0.9±0.1 g/cm3 |
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| Boiling Point | 439.5±24.0 °C at 760 mmHg |
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| Molecular Formula | C22H36O2 |
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| Molecular Weight | 332.520 |
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| Flash Point | 336.2±18.0 °C |
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| Exact Mass | 332.271515 |
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| PSA | 37.30000 |
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| LogP | 7.95 |
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| Vapour Pressure | 0.0±2.3 mmHg at 25°C |
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| Index of Refraction | 1.498 |
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| Storage condition | −20°C |
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2. Packaging
For powders: normal is 25kgs/Drum or bag, or larger/smaller package as request.
For liquids: normal 25kgs/drum, 180-300kgs/bucket, or IBC, determined by the nature of the product.
Or smaller package 1kg/bottle, 10kgs/bottle as request.
3. Shipping
4. Contact information
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