Other Name:
4-Hydroxypyrazolo[3,4-d]pyrimidine;
1H-Pyrazolo[3,4-d]pyrimidin-4-ol;
HPP
Molecular formula:
C5H4N4O
InChI:
1S/C5H4N4O/c10-5-3-1-8-9-4(3)6-2-7-5/h1-2H,(H2,6,7,8,9,10)
Water soluble:
0.35G/L(25ºC)
Descriptors:
White or white crystalline powder, melting point 383-384℃, soluble in lye, very slightly soluble in water and general organic solvents, insoluble in chloroform, ether.
Safety instructions:
S24: avoid contact with skin.
S26: in case of contact with eyes, rinse immediately with plenty of water and send for medical treatment.
S45: if you have an accident or feel unwell, seek immediate assistance from your doctor (preferably with the product container label).
S36/37/39: wear appropriate protective clothing, gloves and use protective glasses or face mask.
Dangerous goods label:
Toxic substances
Hazard category code:
R25: toxic to swallow.
R43: allergic reactions can occur in contact with skin.
R36/37/38: irritant to eyes, respiratory tract and skin.
Transport number of dangerous goods:
UN2811
The product application:
Antigout. For primary or secondary hyperuricemia, such as gout, acute or chronic leukemia.
Production methods and others:
Will cyanoacetic acid ethyl ester, triethyl orthoformate and acetic anhydride in the reaction tank back 4 h, condensation get alpha - ethoxy methyl cyanide ethyl acetate: it dissolve in ethanol, to join the hydrazine hydrate, heating reflux reaction 6 h, 3 - amino - 4 - ethoxy carbonyl pyrazole, finally heating reflux reaction with formamide 8 h, cyclization don't Piao alcohol. Dissolved in distilled water, active carbon decoloring, refined don't Piao alcohol. The cyanoacetic acid ethyl ester, the total yield of 41.8
China
