Phenyl-2-nitropropene is a chemical compound with the chemical formula is C9H9NO2. It can be produced by the reaction of benzaldehyde and nitroethane in the presence of a basic catalyst. In this reaction, the base deprotonates nitroethane to form a resonance stabilized anion. This anion nucleophilically adds to the aldehyde forming a beta nitro alcohol, which is subsequently dehydrated to yield the nitroalkene. This reaction is known as a nitroaldol reaction. Phenyl-2-nitropropene can be reduced in the presence of a catalyst to produce phenylacetone, which is a controlled precursor of methamphetamine. However, with lithium aluminium hydride it can simply be reduced to directly form amphetamine in moderate yields.
Synthesis of phenyl-2-nitropropene
English name 1-phenyl-2-nitro-e
CAS number 705-60-2
Molecular formula C9H9NO2
The molecular weight of 163.17300
Accurate mass 163.06300
PSA 45.82000
LOGP 2.84730
Appearance and properties:
The orange needle
Density:
1.141 g/cm3
Boiling point:
263 DHS C at 760 mmHg
Melting point:
DHS C. 63-65
Flash:
115.7 DHS C
The refractive index:
1.586
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