Epimagnolin B

Name

(1R,3aR,4S,6aR)-1-(3,5-Dimethoxyphenyl)-4-(3,4,5-trimethoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan

Synonym

More Synonyms

Description

Epimagnolin B is a bisepoxylignan isolated from Magnolia fargesii, with anti-inflammatory activity and antiallergic effects. Epimagnolin B inhibits NO production in LPS-activated microglia. Epimagnolin B exhibited antiallergic effects[1][2].

Related Catalog

In Vitro

Epimagnolin B exhibits antiallergic effects without affecting the viability of BMMCs[1].

References

[1]. Kim JY, et al. In vitro anti-inflammatory activity of lignans isolated from Magnolia fargesii. Bioorg Med Chem Lett. 2009 Feb 1;19(3):937-40.

[2]. Xing Zhang, et al. Bioassay-guided isolation of bisepoxylignans from the flower buds of Magnolia biondii Pamp and their antiallergic effects.  RSC Advances. July 2017;7(54):34236-34243.

Density

1.2±0.1 g/cm3

Boiling Point

548.2±50.0 °C at 760 mmHg

Molecular Formula

C23H28O7

Molecular Weight

416.464

Flash Point

220.9±30.0 °C

Exact Mass

416.183502

LogP

2.75

Vapour Pressure

0.0±1.4 mmHg at 25°C

Index of Refraction

1.542