Names
Name Polygalaxanthone III
Synonym More Synonyms
Polygalaxanthone III Biological Activity
Description Polygalaxanthone III is extracted from polygala tenuifolia wild, has inhibitory effect towards CYP450 enzyme. Polygalaxanthone III inhibits chlorzoxazone 6-hydroxylation catalyzed by CYP2E1 with an IC50 of 50.56 μM[1].
Related Catalog
Signaling Pathways >> Metabolic Enzyme/Protease >> Cytochrome P450
Research Areas >> Inflammation/Immunology
References
[1]. Li ZL, et al. Effect of oligosaccharide esters and polygalaxanthone Ill from Polygala tenuifolia willd towards cytochrome P450. Zhongguo Zhong Yao Za Zhi. 2014 Nov;39(22):4459-63.
Chemical & Physical Properties
Density 1.83
Boiling Point 973.2±65.0 °C at 760 mmHg
Melting Point 180-183℃
Molecular Formula C25H28O15
Molecular Weight 568.481
Flash Point 327.7±27.8 °C
Exact Mass 568.142822
LogP -0.31
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.765
Safety Information
Safety Phrases S24/25
Synonyms
D-Glucitol, 1,5-anhydro-6-O-[(2R,3R,4R)-tetrahydro-3,4-dihydroxy-4-(hydroxymethyl)-2-furanyl]-1-C-(1,3,6-trihydroxy-7-methoxy-9-oxo-9H-xanthen-2-yl)-, (1S)-
(1S)-1,5-Anhydro-6-O-[(2R,3R,4R)-3,4-dihydroxy-4-(hydroxymethyl)tetrahydro-2-furanyl]-1-(1,3,6-trihydroxy-7-methoxy-9-oxo-9H-xanthen-2-yl)-D-glucitol
polygalaxanthone III
China
