Product Name: Mafenide hydrochloride
Synonyms: masudin;morfanil;α-Amino-p-toluenesulfonamide hydrochloride, Homosulfanilamide hydrochloride;4-(Aminomethyl)benzenesulfonamide hydrochloride,99+%;4-Homosulfanilamide hydrochloride ,98%;BenzenesulfonaMide, 4-(aMinoMethyl)-, hydrochloride;alpha-Amino-p-toluenesulfonamide Hydrochloride Mafenide Hydrochloride;BenzenesulfonaMide,4-(aMinoMethyl)-, hydrochloride (1:1)
CAS: 138-37-4
MF: C7H11ClN2O2S
MW: 222.69
EINECS: 205-325-3
Product Categories:
Mol File: 138-37-4.mol
Mafenide hydrochloride Structure
Mafenide hydrochloride Chemical Properties
Melting point 261-263 °C(lit.)
form neat
Merck 13,5671
InChIKey SIACJRVYIPXFKS-UHFFFAOYSA-N
CAS DataBase Reference 138-37-4(CAS DataBase Reference)
Safety Information
Hazard Codes Xn
Risk Statements 42/43
Safety Statements 22-36/37-45
WGK Germany 2
RTECS XT5425000
HS Code 29350090
Toxicity LD50 in rats, mice (mg/kg): 1170, 900 i.v. (Skulan, Hoppe)
MSDS Information
Provider Language
SigmaAldrich English
Mafenide hydrochloride Usage And Synthesis
Uses Antibacterial;Inhibitor of folic acid biosynthesis
Purification Methods Crystallise the salt from dilute HCl or 95% EtOH and dry it in a vacuum at 100o. It is an antibacterial. [Miller et al. J Am Chem Soc 62 2099 1940, Bergeim & Barker J Am Chem Soc 66 1459 1944.] The sulfate salt has m 254-255o (from aqueous EtOH). [Beilstein 14 III 2223, 14 IV 2799.]
China
