1-(5-Isoquinolinylsulfonyl)homopiperazine dihydrochloride, Fasudil dihydrochloride

Name

1-(5-Isoquinolinylsulfonyl)homopiperazine dihydrochloride, Fasudil dihydrochloride

Synonym

More Synonyms

Molecular Formula

C14H21Cl2N3O3S

Molecular Weight

382.306

Exact Mass

381.068054

PSA

79.91000

LogP

4.10600

Personal Protective Equipment

Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

RIDADR

NONH for all modes of transport

RTECS

HM4031166

HS Code

2942000000

HS Code

2942000000

Vasodilator actions of HA1077 in vitro and in vivo putatively mediated by the inhibition of protein kinase.

Br. J. Pharmacol. 98 , 1091, (1989)

The in vitro and in vivo vasorelaxant effects of HA1077, 1-(5-isoquinolinesulphonyl)-homopiperazine HCl, a novel vasodilator were examined. The inhibitory effects of HA1077 on contractile responses to...

A new type of vasodilator, HA1077, an isoquinoline derivative, inhibits proliferation of bovine vascular smooth muscle cells in culture.

J. Pharmacol. Exp. Ther. 259 , 738, (1991)

The effects of a newly developed vasodilator agent, HA1077 [1-(5-isoquinolinesulfonyl)-homopiperazine hydrochloride], were investigated on the proliferation of cultured bovine aortic vascular smooth m...

Effects of HA1077, a protein kinase inhibitor, on myosin phosphorylation and tension in smooth muscle.

Eur. J. Pharmacol. 195 , 267, (1991)

We examined the effects of HA1077, a potent inhibitor of protein kinases in vitro, on the relationship between tension and myosin-light chain (MLC20) phosphorylation in the initial phase of contractio...

HA-1077 (hydrochloride)

Fasudil dihydrochloride

5-(1,4-Diazepan-1-ylsulfonyl)isoquinoline dihydrochloride hydrate

HA-1077 dihydrochloride

Isoquinoline, 5-[(hexahydro-1H-1,4-diazepin-1-yl)sulfonyl]-, hydrochloride, hydrate (1:2:1)

HA-1077 dihydrochloride,1-(5-Isoquinolinylsulfonyl)homopiperazine dihydrochloride,Fasudil dihydrochloride