Product Name: Ginseng extract
Synonyms: ginsenoside from ginseng root;Ginseng america;Ginseng, Panax quinquefolium, ext.;Ginseng Monosomic saponins Rh,;Oriental Ginseng P.E;Ginseng saponin;PANAX GINSENG ROOT EXTRACT;Panaxquinquefoliusextract
CAS: 90045-38-8
MF: C15H24N2O
MW: 248.37
EINECS: 289-898-5
Product Categories: Natural Plant Extract;Plant extract;-
Mol File: Mol File
Ginseng extract Structure
Ginseng extract Chemical Properties
Safety Information
HS Code 2938900000
MSDS Information
Ginseng extract Usage And Synthesis
Uses ginseng extract (Panax sp.) is considered tonic and nourishing because of its vitamin and hormone content. It seems to aid in diminishing wrinkles and helps dry skin. It is also said to promote skin elasticity, perhaps by stimulating sterol and protein production. other claims include skin rejuvenating, oxygenating, and stimulating properties. Folkloric remedies cite use for boils, bruises, sores, and swellings. This root’s active components are called ginsenosides and these are said to be responsible for revitalizing and reactivating epidermal cells. other important constituents include saponins, mucin, and vitamin B. The extract comes from the root. ginseng has been associated with many allergic skin reactions.
Indications Panax ginseng describes the root from two species of plants, Asian ginseng (Panax ginseng) and American ginseng (Panax quinquefolius), popularly used for improving stamina and providing a sense of well-being. The terms red and white ginseng refer to how the root is processed, not the species of origin. Red ginseng roots are steam-cured prior to drying, while white ginseng is bleached and dried. Panax ginsengs contain triterpenoid saponins called ginsenosides (also called panaxosides), of which up to 18 types are recognized as having differing and sometimes opposing pharmacological properties.
Siberian ginseng (Eleutherococcus senticosus) should not be confused with Panax ginseng.Although it belongs to the same plant family (Araliaceae), it is a much larger, more abundant, and consequently less expensive plant. Like Panax ginseng, however, it is used as a tonic and adaptogen, a nonmedical term meaning that it helps the body adapt to stress in a variety of ways. Siberian ginseng does contain saponins (eleutherosides) but no ginsenosides. To date, in spite of its popularity, there is little conclusive evidence of clinical efficacy.
General Description Major components are named the ginsenosides. The chemical constituents of ginseng are called ginsenosides or panaxosides. A total of 12 of these have been isolated but are present in such small quantities that purification is difficult. Sterols, flavonoids, proteins, and vitamins (B1, B2, B12, pantothenic acid, niacin, and biotin) are also components with pharmacological activity. The chemistry of ginseng gives a good example of how different compounds in one herb can have opposing pharmacological effects. Ginsenoside Rb-1 acts as a CNS depressant, anticonvulsant, analgesic, and antipsychotic, prevents stress ulcers, and accelerates glycolysis and nuclear RNA synthesis. Ginsenoside Rg-1 stimulates the CNS, combats fatigue, is hypertensive, and aggravates stress ulcers.
Additionally, ginsenosides Rg and Rg-1 enhance cardiac performance, whereas Rb depresses that function. Some of the other ginsenosides display antiarrhythmic activity similar to that of the calcium channel blocker verapamil and amiodarone. Ginseng is popularly believed to enhance concentration, stamina, alertness, and the ability to do work. Longer-term use in elderly patients is claimed to enhance “well-being.”.
Mechanism of action Ginsenosides are thought to be the active principles in Panax ginseng root. The various subtypes can have opposing pharmacological actions: Rg1 stimulates the central nervous system (CNS) and elevates blood pressure, while Rb1 does just the opposite. Somehow these multiple ginsenoside constituents are thought to act in concert to provide increased stamina. In addition, these compounds have antiplatelet aggregation effects and antioxidant properties, and they may stimulate the immune system.
Anticancer Research Ginseng can refer to either white or red ginseng, and herbal preparations varyaccording to the type. In European herbal medicine, ginseng is powdered into300 mg/capsule, with 2–3 capsule/day dosage (Lust 2014). For ginseng in dryextract, 15 ml of oral liquid is given once daily. Each 15 ml of oral liquid contains140 mg of dry extract (Kapoor 2000). American ginseng is also listed as an ingredientin some soft drinks, and its oil and extracts are used in soap and cosmetics(Gupta et al. 2004). There is a little evidence in terms of clinical research to supportginseng treating breast cancer (Shin et al. 2000). However, research conducted inChina suggests that patients treated with any form of ginseng maintained betterpsychological condition. Thus, it might be more appropriate to say it has benefits interms of supporting and minimising damage from the cancer drug tamoxifen intreatment (Cui et al. 2006).
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