ChemicalBook Product Catalog Analytical Chemistry Standard Standard Substance CYCLOSPORIN D

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CYCLOSPORIN D

$ 1.00 /1KG

Min. Order1KG
Purity95-99%
Cas No 63775-96-2
Supply Ability1ton
Update time2020-01-03

career henan chemical co

5YR

China

Chemical Properties

Product Name	CYCLOSPORIN D
CAS No	63775-96-2
EC-No	200-258-5
Min. Order	1KG
Purity	95-99%
Supply Ability	1ton
Release date	2020/01/03

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CYCLOSPORIN D Basic information

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Product Name:

CYCLOSPORIN D

Synonyms:

Cyclosporine EP Impurity D;CYCLOSPORIN D;Val2-cyclosporine;(3R,4R)-3-Hydroxy-N-methyl-5-[(E)-1-propenyl]-cyclo(L-Leu-L-Val-Sar-N-methyl-L-Leu-L-Val-N-methyl-L-Leu-L-Ala-D-Ala-N-methyl-L-Leu-N-methyl-L-Leu-N-methyl-L-Val-);(3R,4R)-3-Hydroxy-N-methyl-5-[(E)-1-propenyl]cyclo(L-Leu-L-Val-Sar-N-methyl-L-Leu-L-Val-N-methyl-L-Leu-L-Ala-D-Ala-N-methyl-L-Leu-N-methyl-L-Leu-N-methyl-L-Val-);Cyclo[L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-3-hydroxy-N,4-dimethyl-L-2-amino-6-octenoyl-L-valyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl];7-L-Valinecyclosporin A;Cyclosporine IMpurity-D

CAS:

63775-96-2

MF:

C63H111N11O12

MW:

1214.62

EINECS:

806-434-4

Product Categories:

ACTIVE PHARMACEUTICAL INGREDIENTS;Intermediates & Fine Chemicals;Anti-cancer&immunity;Peptides;Pharmaceuticals

Mol File:

63775-96-2.mol

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CYCLOSPORIN D Chemical Properties

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Melting point

148-1510C

alpha

D20 -245° (c = 0.52 in CHCl3); D20 -211° (c = 0.51 in methanol)

Boiling point

1294.7±65.0 °C(Predicted)

density

1.015±0.06 g/cm3(Predicted)

9 °C

storage temp.

-20°C Freezer

pka

13.22±0.70(Predicted)

form

Colorless to off-white crystalline solid.

InChIKey

YJDYDFNKCBANTM-QCWCSKBGSA-N

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Safety Information

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Hazard Codes

F,Xn,T

Risk Statements

11-20/21/22-36-39/23/24/25-23/24/25

Safety Statements

16-36/37-45-7

RIDADR

UN 1648 3 / PGII

WGK Germany

HS Code

29419090

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MSDS Information

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CYCLOSPORIN D Usage And Synthesis

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Chemical Properties

Colorless Crystalline Solid

Uses

A group of nonpolar cyclic oligopeptides with immunosupppressant activity.

Uses

Cyclosporin D is a minor analogue of the cyclosporin family which is only weakly immunologically active. Cyclosporin D is a potent inhibitor of tumour-promoting phorbol esters on mouse skin in vivo, and a potent inhibitor of calcium/calmodulin-dependent EF-2 phosphorylation in vitro.

Uses

Cyclosporin D is a minor analogue of the cyclosporin family which is only weakly immunologically active. Cyclosporin D is a potent inhibitor of tumor-promoting phorbol esters on mouse skin in vivo, and a potent inhibitor of calcium/calmodulin-dependent EF-2 phosphorylation in vitro.

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