Product Name: HISPIDULIN
Synonyms: Hispidulin, >99%;SCUTELLAREIN 6-METHYL ETHER;4',5,7-Trihydroxy-6-methoxyflavone;5,7-Dihydroxy-2-(4-hydroxyphenyl)-6-methoxy-4H-1-benzopyran-4-one;6-Methoxyapigenin;6-Methylscutellarein;Hispidulin(Dinatin);Methoxyapigenin
CAS: 1447-88-7
MF: C16H12O6
MW: 300.26
EINECS:
Product Categories: Miscellaneous Natural Products
Mol File: 1447-88-7.mol
HISPIDULIN Structure
HISPIDULIN Chemical Properties
Melting point 291-292 °C
Boiling point 601.5±55.0 °C(Predicted)
density 1.512±0.06 g/cm3(Predicted)
storage temp. Desiccate at -20°C
solubility DMSO: soluble20mg/mL, clear
pka 6.51±0.40(Predicted)
form powder
color white to beige
Safety Information
Hazard Codes Xn
Risk Statements 22
WGK Germany 3
RTECS DJ2996000
MSDS Information
HISPIDULIN Usage And Synthesis
Definition ChEBI: A monomethoxyflavone that is scutellarein methylated at position 6.
Biological Activity Partial positive allosteric modulator at the benzodiazepine receptor (IC 50 = 1.3 μ M for inhibition of flumazenil binding); natural sage flavone. Stimulates GABA-induced chloride currents in Xenopus oocytes expressing α 1 α 2-, α 3-, α 5- or α 6- β 2 γ 2S GABA A receptors. Brain penetrant; oral administration reduces seizures in a gerbil model of epilepsy. Also has antifungal, antiproliferative, antioxidant and antithrombotic properties.
China
