Name | 7,4'-Dihydroxyflavone |
Description | 7,4'-Dihydroxyflavone (4',7-Dihydroxyflavone) can induce transcription of nodulation (nod) genes in Rhizobium meliloti. It has inhibitory activities against COX-2. |
In vitro | Root exudate from 3-day-old alfalfa seedlings was purified and then assayed for biological activity with a nodABC-lacZ fusion in R. meliloti. Indentities of major nod inducers were established by spectroscopic analyses (ultraviolet/visible, proton nuclear magnetic resonance, and mass spectroscopy) and comparison with authentic standards. Major nod inducers, which were identified as 4',7-Dihydroxyflavone, 4'-7-dihydroxyflavanone, and 4,4'-dihydroxy-2'-methoxychalcone, were released from seedling roots at 54, 22, and 20 picomole.plant(-1).day(-1), respectively. Luteolin was not found in these root exudates. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO : 250 mg/mL (983.32 mM)
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Keywords | Inhibitor | 7,4'-Dihydroxyflavone | 7,4'Dihydroxyflavone | inhibit | Nuclear factor-κB | NF-κB | CCR | Nuclear factor-kappaB | 7,4' Dihydroxyflavone | CC chemokine receptor |
Inhibitors Related | Bismuth Subsalicylate | Ibuprofen | Sodium 4-phenylbutyrate | Acetaminophen | Valproic Acid | Curcumin | Glucosamine | Lidocaine hydrochloride | Indole-3-carbinol | Paradol | Diallyl disulfide | Salicylic acid |
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