3--Phenyl-N-(2,2,2-trichloro-1-((((4-chlorophenyl)amino)carbonothioyl)amino)ethyl)acrylamide | China | Manufacturer

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Product Name:

LY2940680

Synonyms:

Taladegib (LY2940680);4-Fluoro-N-methyl-N-[1-[4-(1-methyl-1H-pyrazol-5-yl)-1-phthalazinyl]-4-piperidinyl]-2-(trifluoromethyl)benzamide LY 2940680;LY2940680 (Taladegib);Taladegib;Taladegib hydrochloride;4-Fluoro-N-methyl-N-(1-(4-(1-methyl-1H-pyrazol-5-yl)phthalazin-1-yl)piperidin-4-yl)-2-(trifluo;LY2940680;4-Fluoro-N-methyl-N-[1-[4-(1-methyl-1H-pyrazol-5-yl)-1-phthalazinyl]-4-piperidinyl]-2-(trifluoromethyl)benzamide

CAS:

1258861-20-9

MF:

C26H24F4N6O

MW:

512.51

EINECS:

Product Categories:

-;Inhibitors

Mol File:

1258861-20-9.mol

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LY2940680 Chemical Properties

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Boiling point

703.5±60.0 °C(Predicted)

density

1.39

pka

7.94±0.30(Predicted)

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Safety Information

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MSDS Information

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LY2940680 Usage And Synthesis

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Uses

Smoothened (Smo) is a GPCR-like receptor that, with Patched, mediates hedgehog (Hh) signaling to regulate gene expression through the Gli transcription factors. LY2940680 is an antitumor agent that binds to the human Smo receptor and inhibits Sonic Hh-induced Gli1 expression (IC50 = ~2.4 nM in vitro). The potential anticancer activity of LY2940680 is currently under clinical investigation.[Cayman Chemical]

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LY2940680 Preparation Products And Raw materials

Product Name	LY2940680
CAS No	1258861-20-9
EC-No
Min. Order	1KG
Purity	99%
Supply Ability	100kgs
Release date	2019/12/20

LY2940680

Company Profile Introduction

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