English name avanafil
Avanafil is a PDE5 inhibitor approved for erectile dysfunction by the FDA on April 27, 2012 and by EMA on June 21, 2013. Avanafil is known by the trademark names Stendra and Spedra and was developed by Vivus Inc. In July 2013 Vivus announced partnership with Menarini Group, which will commercialise and promote Spedra in over 40 European countries plus Australia and New Zealand. Avanafil acts by inhibiting a specific phosphodiesterase type 5 enzyme which is found in various body tissues, but primarily in the corpus cavernosum penis, as well as the retina. Other similar drugs are sildenafil, tadalafil and vardenafil. The advantage of avanafil is that it has very fast onset of action compared with other PDE5 inhibitors. It is absorbed quickly, reaching a maximum concentration in about 30–45 minutes. About two-thirds of the participants were able to engage in sexual activity within 15 minutes.
CAS number 330784-47-9
Molecular formula C23H26ClN7O3
The molecular weight of 483.95100
Accurate mass 483.17900
PSA 125.39000
LOGP 2.96070
5F-ADB
5F-AEB
5F-MDMB-2201
5F-AB-FUPPYCA
5F-CUMYL-PINACA
5-MEO-MIPT
A-PPP
Hexen
nep
BK-2C-B
BUFF
4-CL-PVP
2-Bromo-LSD
2-A1MP
4-CEC
4-CDC
4-EMC
4-MPD
3-MEO-PCP
DIBUTYLONE
ETIZOLAM
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eutylone
2fdck
5fmdmb2201
4fadb
hep
mdpep
ebk
ndh
Lidocaine, procaine, tetracaine, bupivacaine, ropivacaine,Dimethocaine
Sildenafil, tardanafil, vardenafil,
sarms:MK-2866
MK-677
AndarineS-4
GW501516
SR9009
YK11
LGD4033
RAD-140
LGD-3303
AICAR
testosterone:
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