PD 169316

PD 169316 Basic information

Product Name:

PD 169316

Synonyms:

152121-53-4;PD 169316 - CAS 152121-53-4 - Calbiochem;4-[4-(4-Fluorophenyl)-2-(4-nitrophenyl)-1H-imidazol-5-yl]pyridine;4-[5-(4-fluorophenyl)-2-(4-nitrophenyl)-1H-iMidazol-4-yl]pyridine;Pyridine, 4-[4-(4-fluorophenyl)-2-(4-nitrophenyl)-1H-iMidazol-5-yl]-;PD169316/PD-169316;4-[4-(4-Fluorophenyl)-2-(4-nitrophenyl)-1H-imidazol-5-yl]pyridine PD 169316;PD 169316 4-[4-(4-Fluorophenyl)-2-(4-nitrophenyl)-1H-imidazol-5-yl]pyridine

CAS:

MF:

C20H13FN4O2

MW:

360.347

EINECS:

 

Product Categories:

-;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Protein Kinase Inhibitors and Activators;Inhibitors

Mol File:

152121-53-4.mol

 

PD 169316 Chemical Properties

storage temp. 

2-8°C

solubility 

DMSO: >10mg/mL

form 

solid

color 

light orange

 

Safety Information

Hazard Codes 

Xn

Risk Statements 

22-37/38-41

Safety Statements 

26-39

RIDADR 

UN 2811 6.1/PG 3

WGK Germany 

3

MSDS Information

 

PD 169316 Usage And Synthesis

Uses

PD 169316 is a highly selective, potent inhibitor of p38 MAP kinase. PD 169316 inhibits transforming growth factor β-induced Smad signaling in human ovarian cancer cells. PD 169316 acts as an an endogenous suppressor of apoptosis by mimicking CD9, a membrane tetraspanin. Studies show that PD 169316 reduces myocardial ischemia/reperfusion induced voltage-dependent anion channel(VDAC) phosphorylation

 

PD 169316 Preparation Products And Raw materials