Iopromide

Product Name:

Iopromide

Synonyms:

1,3-Benzenedicarboxamide, N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-5-[(methoxyacetyl)amino]-N-methyl-;Ultravist;Ultravist 300;Ultravist 370;ZK 35760;N,N'-Bis(2,3-dihydroxypropyl)-2,4,6-triiodo-5-(2-methoxyacetylamino)-N-methylisophthalamide;N,N'-Bis(2,3-dihydroxypropyl)-2,4,6-triiodo-5-[(methoxyacetyl)amino]-N-methyl-1,3-benzenedicarboxamide;Proscope

CAS:

MF:

C18H24I3N3O8

MW:

791.11

EINECS:

277-385-9

Product Categories:

Amines;Aromatics;Diagnostic;Intermediates & Fine Chemicals;Pharmaceuticals;Isotope Labelled Compounds;-

Mol File:

73334-07-3.mol

 

Iopromide Chemical Properties

Melting point 

broad (160?C transition)

storage temp. 

Hygroscopic, -20?C Freezer, Under Inert Atmosphere

solubility 

Freely soluble in water and in dimethyl sulfoxide, practically insoluble in ethanol (96 per cent) and in acetone.

form 

neat

Stability:

Hygroscopic

CAS DataBase Reference

73334-07-3(CAS DataBase Reference)

 

Safety Information

Hazard Codes 

N

Risk Statements 

50/53

Safety Statements 

60-61

RIDADR 

UN 3077 9 / PGIII

WGK Germany 

3

RTECS 

CZ2230000

HS Code 

2924296000

Toxicity

LD50 in mice, rats (g iodine/kg body weight): 16.5, 11.4 i.v. (Muetzel)

MSDS Information

 

Iopromide Usage And Synthesis

Chemical Properties

White Solid

Uses

Contrast molecule

Uses

Labelled Iopromide. Nonionic, injectable radio-contrast medium. Diagnostic aid (radiopaque medium).

Definition

ChEBI: A dicarboxylic acid diamide that consists of N-methylisophthalamide bearing three iodo substituents at positions 2, 4 and 6, a methoxyacetyl substituent at position 5 and two 2,3-dihydroxypropyl groups attached to the amide nitrogens. A ater soluble x-ray contrast agent for intravascular administration.

Brand name

Ultravist (Berlex).

General Description

Iopromide is a low-osmolar,nonionic monomer with 48% bound iodine content. It is indicatedfor use in angiography, excretory urography, andnumerous CT procedures.