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Benidipine hydrochloride
$ 1.00
/1KG
- Min. Order1KG
- Purity98%
- Cas No91599-74-5
- Supply Ability200kg
- Update time2019-09-02
career henan chemical co
VIP8Y
China
Since:2014-12-17
Address:Zhengzhou High tech Zone, Henan Province, China
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Chemical Properties
| Product Name | Benidipine hydrochloride |
| CAS No | 91599-74-5 |
| EC-No | |
| Min. Order | 1KG |
| Purity | 98% |
| Supply Ability | 200kg |
| Release date | 2019/09/02 |
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Product Name:
Benidipine hydrochloride
Synonyms:
Conipros;rac-(4R*)-1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylic acid 3-methyl 5-[(3R*)-1-benzylpiperidine-3-yl]·hydrochloride;(4R)-rel-1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylicacid3-methyl5-[(3R)-1-(phenylmethyl)-3-piperidinyl]esterhydrochloride;rac Benidipine Hydrochloride;Benidipine hydrochlo;3,5-Pyridinedicarboxylicacid, 1,4-dihydro-2,6-diMethyl-4-(3-nitrophenyl)-, 3-Methyl5-[(3R)-1-(phenylMethyl)-3-piperidinyl] ester, hydrochloride (1:1), (4R)-rel-;(4R)-rel-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 3-methyl 5-[(3R)-1-(phenylmethyl)-3-piperidinyl] ester, hydrochloride (1:1);(4R)-rel-3,5-Pyridinedicarboxylic acid
CAS:
91599-74-5
MF:
C28H31N3O6
MW:
505.56
EINECS:
663-500-3
Product Categories:
Antihypertensive;Intermediates & Fine Chemicals;Pharmaceuticals;Aromatics;Chiral Reagents;Heterocycles;-;Inhibitors
Mol File:
91599-74-5.mol
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Benidipine hydrochloride Chemical Properties
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Melting point
199-201°C
storage temp.
Desiccate at RT
solubility
DMSO: ≥20mg/mL
pka
7.34(at 25℃)
form
powder
color
yellow
InChIKey
DGVVISBYHUXFIU-UHFFFAOYSA-N
CAS DataBase Reference
91599-74-5(CAS DataBase Reference)
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Safety Information
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Hazard Codes
T
Risk Statements
25
Safety Statements
45
RIDADR
UN 2811 6.1 / PGIII
WGK Germany
3
RTECS
US7975657
Toxicity
LD50 orally in male mice: 218 mg/kg (Muto, 1988)
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MSDS Information
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Benidipine hydrochloride Usage And Synthesis
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Description
Benidipine hydrochloride is a new, long acting dihydropyridine calcium antagonist useful in the treatment of hypertension and angina pectoris. In experimental animals, benidipine hydrochloride dose dependently induced hypotension with a potency of 6 and 12 times more than nifedipine and nicardipine, respectively. It also exhibited a slow onset of action.
Chemical Properties
Yellow Crystalline Powder
Originator
Kyowa Hakko (Japan)
Uses
A dihydropyridine calcium channel blocker. Antihypertensive.
Brand name
Coniel
Biological Activity
Orally active antihypertensive agent which displays a wide range of activities in vitro and in vivo . Inhibits L-, N- and T-type Ca 2+ channels. Also inhibits aldosterone-induced mineralocorticoid receptor activation. Exhibits cardioprotective and antiartherosclerotic effects.
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Benidipine hydrochloride Preparation Products And Raw materials
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Company Profile Introduction
Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals. Mainly deals in the sales of: Pharmaceutical intermediates OLED intermediates： Pharmaceutical intermediates; OLED intermediates;
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