Hydrocortisone sodium succinate

Hydrocortisone sodium succinate Basic information

Product Name:

Hydrocortisone sodium succinate

Synonyms:

a-hydrocort;buccalsone;corlan;cortisol,21-(hydrogensuccinate),monosodiumsalt;cortisol,succinate,sodiumsalt;cortisol21-sodiumsuccinate;cortisolsodiumhemisuccinate;cortisolsodiumsuccinate

CAS:

MF:

C25H33O8.Na

MW:

484.52

EINECS:

204-725-5

Product Categories:

Steroid and Hormone;-

Mol File:

125-04-2.mol

 

Hydrocortisone sodium succinate Chemical Properties

Melting point 

169.0-171.2°

storage temp. 

−20°C

solubility 

H₂O: 50 mg/mL

form 

powder

InChIKey

HHZQLQREDATOBM-CODXZCKSSA-M

CAS DataBase Reference

125-04-2(CAS DataBase Reference)

 

Safety Information

WGK Germany 

3

RTECS 

GM9015000

MSDS Information

 

Hydrocortisone sodium succinate Usage And Synthesis

Uses

Hydrocortisone sodium succinate is a derivative of the glucocorticoid Hydrocortisone (H714615). Hydrocortisone Hemisuccinate Sodium is used as an anti-inflammatory agent. Hydrocortisone sodium succinate is widely used in the treatment of asthma, endocrine disorders, dermatological disorders, allergic states, etc.

Uses

Hydrocortisone 21-hemisuccinate is a water-soluble form of the endogenous hormone cortisol. It can bind to glucocorticoid receptors, initiating the transcription of anti-inflammatory and immunosuppressive mediators and inhibiting proinflammatory cytokine activity (IC50 = 6.7 μM for IL-6). It is commonly used to supplement media for long-term epithelial or endothelial cell cultures and to differentiate pluripotent stem cells.

Brand name

A-Hydrocort (Abbott); A-Hydrocort (Hospira); Solu-Cortef (Pharmacia & Upjohn).

 

Hydrocortisone sodium succinate Preparation Products And Raw materials