Erythromycin ethylsuccinate

Product Name:

Erythromycin ethylsuccinate

Synonyms:

ERYTHROMYCIN 2'-(ETHYL BUTANEDIOATE);ERYTHROMYCIN 2'-(ETHYL SUCCINATE);ERYTHROMYCIN ETHYLSUCCINATE;erythrocinethylsuccinate;erythromycin,mono(ethylsuccinate);erythromycin,mono(ethylsuccinate)(ester);Erythromycin Ethylsuccinate-D5;Succinic acid, monoester with erythromycin

CAS:

MF:

C43H75NO16

MW:

862.05

EINECS:

215-033-8

Product Categories:

-;Organics;Interferes with Protein SynthesisAntibiotics;A - KAntibiotics;Antibacterial;Antibiotics A to;Antibiotics A-FAntibiotics;Chemical Structure Class;Macrolides;Mechanism of Action;Spectrum of Activity;ERYPED

Mol File:

1264-62-6.mol

 

Erythromycin ethylsuccinate Chemical Properties

Melting point 

219-224 C

Boiling point 

778.19°C (rough estimate)

density 

1.1417 (rough estimate)

refractive index 

1.5280 (estimate)

Fp 

>110°(230°F)

storage temp. 

2-8°C

solubility 

ethanol: soluble50mg/mL

form 

solid

color 

white

Water Solubility 

Freely soluble in organic solvents, practically insoluble in water

CAS DataBase Reference

1264-62-6

 

Safety Information

Hazard Codes 

Xn,Xi

Risk Statements 

42/43-36/37/38

Safety Statements 

36-26

WGK Germany 

2

RTECS 

WM9800000

HS Code 

29419000

Hazardous Substances Data

1264-62-6(Hazardous Substances Data)

Chemical Properties

ERYTHROMYCIN ETHYLSUCCINATE is crystals

Uses

antibacterial

Brand name

E-Mycin (Pharmacia & Upjohn); E.E.S. (Abbott); Eryped (Abbott); Pediamycin (Ross); Wyamycin (Wyeth).

General Description

Erythromycin ethylsuccinate (EES, Pediamycin, EryPed) isthe ethylsuccinate mixed ester of erythromycin in which the2＇-hydroxyl group of the desosamine is esterified. It isabsorbed as the ester and hydrolyzed slowly in the body toform erythromycin. It is somewhat acid labile, and itsabsorption is enhanced by the presence of food. The ester isinsoluble in water but soluble in alcohol and ether.