Product no. chemwill1TMGL91510
5,7-Dichloro-8-hydroxyquinoline Manufacturer High quality Best price In stock factory 773-76-2 Chloroxine 5,7-Dichloro-8-quinolinol 773-76-2
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5,7-Dichloro-8-hydroxyquinoline CAS 773-76-2
Chloroxine CAS 773-76-2
5,7-Dichloro-8-quinolinol CAS 773-76-2
NMR Spectrum 1H NMR : 90 MHz in CDCl3
Chloroxine, is an impurity of Cioquinol, which is an antifungal and antiprotozoal drug.
Name 5,7-Dichloro-8-hydroxyquinoline
Synonyms 5,7-Dichloro-8-quinolinol; Chloroxine 5,7-dichloroquinolin-8-ol; 5,7-Dichloro-8-hydroxyquinoline; 8-Quinolinol, 5,7-dichloro-; 5,7-Dichloro-8-oxine 5,7-Dichloro-8-quinolinol;Clioquinol EP IMpurity B;5,7-Dichlor-8-hydroxychinolin;5,7-Dichloro-8-hydroquinoline;5,7-Dichloro-8-hydroxyquinolin;5,7-Dichloro-8-oxychinolin;5,7-Dichloro-8-oxyquinoline;5,7-dichloro-8-quinolino
Molecular Structure CAS # 773-76-2, 5,7-Dichloro-8-hydroxyquinoline, 5,7-Dichloro-8-quinolinol, Chloroxine
Molecular Formula C9H5Cl2NO
Molecular Weight 214.05
CAS Registry Number 773-76-2
EINECS 212-258-3
Properties
Melting point 180-183 ºC
MF: C9H5Cl2NO
MW: 214.05
EINECS: 212-258-3
Product Categories: Building Blocks;C8 to C10;Chemical Synthesis;Halogenated Heterocycles;Heterocyclic Building Blocks;CINAZYN;Quinolines, Quinazolines and derivatives;Haloquinolines;Hydroxyquinolines;Quinolines
5,7-Dichloro-8-hydroxyquinoline Chemical Properties
Melting point 178-180 °C(lit.)
Boiling point 305.47°C (rough estimate)
density 1.3320 (rough estimate)
refractive index 1.5500 (estimate)
storage temp. 2-8°C
form Fluffy Powder
color Light beige
HS Code 29334900
Usage And Synthesis
Chemical Properties light beige fluffy powder
Uses H1 antihistamine
Uses Analytical reagent.
Definition ChEBI: Quinolin-8-ol in which the hydrogens at positions 5 and 7 have been substituted by chlorine. An synthetic antibacterial prepared by chlorination of quinolin-8-ol, it is used for the treatment of dandruff and seborrhoeic dermatitis of the scalp.
Brand name Capitrol (Westwood- Squibb).
Purification Methods Crystallise the dichloro-oxine from acetone/EtOH
Preparation Products And Raw materials
Raw materials 8-Hydroxyquinoline-->Basic Orange 2