| CAS: | 4224-70-8 |
| MF: | C6H11BrO2 |
| MW: | 195.05 |
| EINECS: | 224-176-5 |
| Product Categories: | C6;Carbonyl Compounds;omega-Functional Alkanols, Carboxylic Acids, Amines & Halides;Carboxylic Acids;Chemical Synthesis;Organic Building Blocks;Organic acids;Acids & Esters;Bromine Compounds;omega-Bromocarboxylic Acids;Aliphatics;Miscellaneous Reagents;Building Blocks |
| Mol File: | 4224-70-8.mol |
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| 6-Bromohexanoic acid Chemical Properties |
| Melting point | 32-34 °C (lit.) |
| Boiling point | 165-170 °C/20 mmHg (lit.) |
| density | 1.3996 (rough estimate) |
| refractive index | 1.4790 (estimate) |
| Fp | 154 °F |
| storage temp. | Inert atmosphere,2-8°C |
| solubility | methanol: 0.1 g/mL, clear, colorless |
| pka | 4.72±0.10(Predicted) |
| form | Low Melting Crystals |
| color | White to light orange |
| BRN | 1749740 |
| InChIKey | NVRVNSHHLPQGCU-UHFFFAOYSA-N |
| LogP | 1.700 (est) |
| CAS DataBase Reference | 4224-70-8(CAS DataBase Reference) |
| NIST Chemistry Reference | Hexanoic acid, 6-bromo-(4224-70-8) |
| EPA Substance Registry System | Hexanoic acid, 6-bromo- (4224-70-8) |
| 6-Bromohexanoic acid Usage And Synthesis |
| Organic Intermediate | 6-bromohexanoic acid(CAS:4224-70-8), also called 6-bromohexanoic acid or 6-bromo-hexanoic acid, is an organobromine compound comprising hexanoic acid having a bromo substituent at the 6-position. 6-Bromohexanoic acid is used in the preparation of N-acylsulfonamides, diarylthioethers and 2-lithio-1,3-dithian. It is widely used as an intermediate in organic synthesis. Here, we introduced a method for making this compound. |
| Chemical Properties | White to light orange low melting crystals |
| Uses | Employed in a direct preparation of N-acylsulfonamides on treatment with tosyl isocyanate (189278)1 and alkyl ketones from alkyl iodides and metallic strontium.2 |
| Uses | 6-Bromohexanoic acid is used in the preparation of N-acylsulfonamides, diarylthioethers and 2-lithio-1,3-dithian. It is widely used as an intermediate in organic synthesis. |
| Uses | 6-Bromohexanoic acid was used in the preparation of N-acylsulfonamides on treatment with tosyl isocyanate (189278) and alkyl ketones from alkyl iodides and metallic strontium. It was also used in the synthesis of anionic mitomycin C-dextran conjugate (MMC-D), 2-lithio-1,3-dithian and diaryl thioethers. |
| Definition | ChEBI: 6-bromohexanoic acid is an organobromine compound comprising hexanoic acid having a bromo substituent at the 6-position. It is functionally related to a hexanoic acid. |
| Synthesis Reference(s) | Journal of the American Chemical Society, 72, p. 5137, 1950 DOI: 10.1021/ja01167a091 |
| Synthesis | The preparation method of the high purity 6-bromocaproic acid: the exsiccant bromize hydrogen gas is directly fed contain in the organic solvent of 6-caprolactone, exsiccant bromize hydrogen gas usage quantity is 6-caprolactone 1.0-2.0 doubly (mol ratio); Stir, ring-opening reaction takes place, temperature of reaction is 0 ℃ ~ 100 ℃, generates high purity 6-bromocaproic acid. |
Packing &shipping&Payment
Packing:25kg/drum
Shipping:by sea or by air
Payment:T/T,western union,moneygram
Packaging Details drum
Port:Tianjin
Lead Time :
| Quantity(Kilograms) | 1 - 10000 | >10000 |
| Est. Time(days) | 5 | To be negotiated |
Company information
Hebei Mojin Biotechnology Co., Ltd, Our company is a professional in 4'-Methylacetophenone,Levamisole hydrochloride ,N-Methylformamide and other chemical reagents research and development production enterprises. Our business covers more than 30 countries, most of the big customers come from Europe, America and other countries in the world, we can guarantee the quality and price. In recent decades, with the efforts of all employees, we have established many cooperative companies in shandong, henan, guangdong and other places. Our corporate purpose is based on the market, enhance the strength, take the road of scientific and environmental sustainable development, relying on the country. Technology r & d center, increase the investment in r & d, based on the domestic market, expand the international market, manufacturing quality products, sincere service to the society, into a modern, ecological, scientific and technological enterprise world.
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