Product Name:Pyrantel pamoate
CAS Number:22204-24-6
Molecula Formula: C34H30N2O6S
Molecular Weight:594.72
EINECS:244-837-1
Melting Point:266-267 °C
Boiling Point:642.7 °C at 760 mmHg
Flash Point: 356.5 °C
Solubility:<0.1 g/100 mL at 19 °C in water
Appearance: Odorless light yellow to tan crystalline powder
Specification:
| Item |
Specifications |
| Description |
Yellow to tan solid |
| Identification |
|
| A.IR |
The IR spectrum of the sample agrees with IR spectrum of the standard |
| B.UV |
The UV spectrum of the sample agrees with UV spectrum of the Standard |
| C.HPLC |
The retention time of the major peaks due to pyrantel base and pamoic acid of the sample solution correspond to the Standard Solution, as obtained in the Assay |
| Assay |
97.0%~103.0%(dried basis) |
| Pamoic acid |
63.4%~67.3%(dried basis) |
| Limit of iron |
Not more than 0.0075% |
| Residue on ignition |
Not more than0.5% |
| Heavy metals |
Not more than50ppm |
| Organic impurities |
|
| Pyrantel related Compound A |
Not more than0.5% |
| Impurity B |
Not more than0.2% |
| Individual unspecified impurities |
Not more than 0.1% |
| Total unspecified Impurities |
Not more than 0.3% |
| Total impurities |
Not more than 1.0% |
| Loss on drying |
Not more than 2.0% |
| Residual solvent |
|
| Ethanol |
Not more than 4000ppm |
| Ethyl formate |
Not more than 4000ppm |
Function & Application:
Pyrantel pamoate (under US Pharmacopoeia) or Pyrantel Embonate (under European Pharmacopoeia), is used as a
deworming agent in the treatment of hookworms (all species) and roundworms (Ascaris lumbricoides, aka ascarids in
humans) in domesticated animals such as horses, cattle, sheep, pigs, cats, dogs, and many other species. It is a combination
of pyrantel and pamoic acid. Some drug companies pair pyrantel pamoate with praziquantel for tapeworms, and sometimes
febantel for whipworms in order to provide more complete treatment for intestinal parasites in one dose.
China
