名称 | 5,7,4'-Trimethoxyflavone |
描述 | 5,7,4'-Trimethoxyflavone (4',5,7-Trimethoxyflavone) is isolated from Kaempferia parviflora (KP) which is a medicinal plant from Thailand. |
体外活性 | 5,7,4'-Trimethoxyflavone induces apoptosis, as evidenced by increments of sub-G1 phase, DNA fragmentation, annexin-V/PI staining, the Bax/Bcl-xL ratio, proteolytic activation of caspase-3, and degradation of PARP protein. 5,7,4'-Trimethoxyflavone is significantly effective at inhibiting the proliferation of SNU-16 human gastric cancer cells in a concentration-dependent manner. |
存储条件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度 | DMSO : 22.5 mg/mL (72.04 mM)
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关键字 | Apoptosis | poly ADP ribose polymerase | 5,7,4' Trimethoxyflavone | Caspase | inhibit | 5,7,4'Trimethoxyflavone | 5,?7,?4'-?Trimethoxyflavone | Inhibitor | PARP | Endogenous Metabolite | 5,7,4'-Trimethoxyflavone |
相关产品 | Stavudine | 5-Fluorouracil | Myricetin | Meclizine dihydrochloride | Dextran sulfate sodium salt (MW 4500-5500) | Sodium 4-phenylbutyrate | L-Ascorbic acid | Metronidazole | Sorafenib | Tributyrin | Salicylic acid | Oleic acid |
相关库 | 抗癌天然产物库 | 黄酮类天然产物库 | 经典已知活性库 | 神经退行性疾病化合物库 | 中药单体化合物库 | 植物来源化合物库 | 天然产物库 | 高通量筛选天然产物库 | 抗衰老化合物库 | 古代经典名方目录分子库 |