| Name | 5,7,4'-Trimethoxyflavone |
| Description | 5,7,4'-Trimethoxyflavone (4',5,7-Trimethoxyflavone) is isolated from Kaempferia parviflora (KP) which is a medicinal plant from Thailand. |
| In vitro | 5,7,4'-Trimethoxyflavone induces apoptosis, as evidenced by increments of sub-G1 phase, DNA fragmentation, annexin-V/PI staining, the Bax/Bcl-xL ratio, proteolytic activation of caspase-3, and degradation of PARP protein. 5,7,4'-Trimethoxyflavone is significantly effective at inhibiting the proliferation of SNU-16 human gastric cancer cells in a concentration-dependent manner. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (6.4 mM), Sonication is recommended. DMSO : 22.5 mg/mL (72.04 mM), Sonication is recommended.
|
| Keywords | poly ADP ribose polymerase | PARP | Inhibitor | inhibit | Endogenous Metabolite | Caspase-3 | Caspase | Apoptosis | 5,7,4'-Trimethoxyflavone | 5,?7,?4'-?Trimethoxyflavone | 5,7,4'Trimethoxyflavone | 5,7,4' Trimethoxyflavone |
| Inhibitors Related | Sucrose | Aceglutamide | Emtricitabine | 3-Hydroxybutyric acid sodium | Levulinic acid | D(+)-Raffinose pentahydrate | D-(+)-Trehalose dihydrate | Tributyrin | Glycerol | Thymidine | Sodium 2-hydroxybutanoate | Chitosan oligosaccharide |
| Related Compound Libraries | Anti-Tumor Natural Product Library | Flavonoid Natural Product Library | Anti-Neurodegenerative Disease Compound Library | Traditional Chinese Medicine Monomer Library | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Selected Plant-Sourced Compound Library | Natural Product Library | Tobacco Monomer Library | Anti-Aging Compound Library | Bitter Compound library | Ancient Chinese Classical Formulas Compound Library |