Product name: Bimatoprost
CAS: 155206-00-1
English name: 17-PHENYL TRINOR PROSTAGLANDIN F2ALPHA ETHYL AMIDE
Molecular formula: C25H37NO4
Molecular weight: 415.57
Traits: crystalline powder
Melting point: 66-68 ° C
Density: 1.145 g / cm3
Boiling point: 629.8ºC at 760 mmHg
Flash point: 334.7ºC
Refractive index: 1.591
Steam pressure: 9.94E-17mmHg at 25 ° C
Bimatoprost (marketed in the U.S., Canada and Europe by Allergan, under the trade name Lumigan) is a prostaglandin analog/prodrug used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. It reduces intraocular pressure (IOP) by increasing the outflow of aqueous fluid from the eyes.In December 2008, the indication to lengthen eyelashes was approved by the U.S. Food and Drug Administration (FDA); the cosmetic formulation of bimatoprost is sold as Latisse.In 2008-2011, at least three case series suggested that bimatoprost has the ability to reduce adipose (fat) tissue.
Function
1.Bimatoprost is a class of high-performance antihypertensive drugs,
it is unique in pharmacology, is a synthetic prostaglandin amide,
has a strong role in lowering intraocular pressure.
2.Bimatoprost may be through the hydrolysis of free acid
after the role of FP class prostaglandin receptor,
so the treatment of glaucoma than
horse prostaglandin commonly used concentration of 0.03%.