5,6,7,8-TETRAHYDROQUINOLINE
Synonyms: 5,6,7,8-tetrahydro-quinoline;2,3-cyclohexenopyridine
CAS No.: 10500-57-9
Molecular formula: C9H11N
5,6,7, 8-tetrahydroquinoline is an organic compound also known as quinoline or hydroquinoline. The following is an introduction to its nature, use, manufacturing and safety information:
Nature:
-5,6,7, 8-tetrahydroquinoline is a colorless liquid with a distinctive odor.
Its chemical formula is C8H11N and its molecular weight is 121.18 g/mol.
-quinoline is a polar solvent that can dissolve many organic compounds.
Purpose:
-5,6,7, 8-tetrahydroquinoline is widely used in various chemical laboratories and industrial production.
- It can be used as a solvent for organic synthesis reactions and can be used as an extractant for separating and purifying compounds.
-quinoline is also a common ligand that can form stable complexes with metal ions associated with coordination chemistry.
Preparation:
-5,6,7, 8-tetrahydroquinoline can be prepared by a variety of synthetic methods, one of which is commonly prepared by heating a carbamate with sulfite.
- In the reaction, the carbamate is first oxidized to sulfonyl alcohol by sulfite, and then a cyclization reaction occurs to form 4-hydroxyquinoline. Finally, the obtained 4-hydroxyquinoline was reduced to 5,6,7, 8-tetrahydroquinoline.
Safety information:
-5,6,7, 8-tetrahydroquinoline has low toxicity but still needs to be handled with caution.
- It has an irritating effect on the skin and eyes, so it is necessary to take appropriate protective measures when using, such as wearing gloves, goggles, etc.
- When used or handled, good ventilation conditions should be provided to avoid inhaling its vapor or solution.
5,6,7, 8-tetrahydroquinoline should be stored in sealed containers, away from fire sources and oxidants, and avoid exposure and high temperatures.