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Ciprofibrate

$ 1.00 /1kg

Min. Order1g
Purity99%
Cas No52214-84-3
Supply Ability100KG
Update time2019-07-06

career henan chemical co

career henan chemical co

7YR

China

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Chemical Properties

Product Name	Ciprofibrate
CAS No	52214-84-3
EC-No
Min. Order	1g
Purity	99%
Supply Ability	100KG
Release date	2019/07/06

Ciprofibrate Basic information

Product Name:	Ciprofibrate
Synonyms:	2-(p-(2,2-dichlorocyclopropyl)phenoxy)-2-methylpropionicacid;2-[4-(2，2-Dichlom-cyclopropyl)phenoxy]-2-methy\|propanoic acid;Cipml;Lipanor;Modalim;Win-35833;2-[4-(2,2-Dichlorocyclopropyl)phenoxy]-2-methylpropionic acid;Ciprofibric acid
CAS:	52214-84-3
MF:	C13H14Cl2O3
MW:	289.15
EINECS:	257-744-6
Product Categories:	Intracellular receptor;API
Mol File:	52214-84-3.mol

Ciprofibrate Chemical Properties

Melting point	114-116°
Boiling point	401.74°C (rough estimate)
density	1.2576 (rough estimate)
refractive index	1.5209 (estimate)
storage temp.	2-8°C
solubility	Practically insoluble in water, freely soluble in anhydrous ethanol, soluble in toluene.
Merck	14,2313
CAS DataBase Reference	52214-84-3(CAS DataBase Reference)

Safety Information

Hazard Codes	T
Risk Statements	45
Safety Statements	53-22-36/37/39-45
WGK Germany	3
RTECS	UF0880000

MSDS Information

Provider	Language
Ciprofibrate	English
SigmaAldrich	English

Ciprofibrate Usage And Synthesis

Chemical Properties	Off-White to Pale Beige Solid
Uses	Ciprofibrate is a hypolipemic agent, related structurally to Clofibrate (C586910). Ciprofibrate is used as an antilipemic.
Uses	antihyperlipidemic
Uses	Peroxisome proliferator-activated receptor α (PPARα) is a ligand-activated transcription factor involved in the regulation of lipid homeostasis. Activation of PPARα results in expression of a variety of genes, particularly those involved in fatty acid β-oxidation, binding, and transport. Ciprofibrate activates PPARα with an EC50 value of 20 μM and only marginally affects PPARγ (EC50 = >300 μM). It has been shown to lower adipose tissue weight and reduce plasma insulin concentrations in obese rats and has been used clinically in the treatment of dyslipidemia. Ciprofibrate reportedly stimulates cholesteryl ester transfer protein expression and improves the flow of cholesterol through the indirect reverse cholesterol transport system, preserving plasma HDL.

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