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ChemicalBook Product Catalog D-ERYTHRO-SPHINGOSINE

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D-ERYTHRO-SPHINGOSINE

$ 1.00 /1kg

Min. Order1g
Purity99%
Cas No123-78-4
Supply Ability100KG
Update time2019-07-06

career henan chemical co

career henan chemical co

7YR

China

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Chemical Properties

Product Name	D-ERYTHRO-SPHINGOSINE
CAS No	123-78-4
EC-No
Min. Order	1g
Purity	99%
Supply Ability	100KG
Release date	2019/07/06

D-ERYTHRO-SPHINGOSINE Basic information

Product Name:	D-ERYTHRO-SPHINGOSINE
Synonyms:	SPHINGOSINE;SPHINGOSINE, C18 CHAIN;SPHINGOSINE, D-ERYTHRO;TRANS D-THREO-SPHINGOSINE;TRANS D-ERYTHRO-SPHINGOSINE;TRANS-D-ERYTHRO-2-AMINO-4-OCTADECENE-1,3-DIOL;BRAIN SPHINGOSINE;BRAIN, BOVINE
CAS:	123-78-4
MF:	C18H37NO2
MW:	299.49
EINECS:	204-651-3
Product Categories:	Mixed Fatty Acids;Fatty Acid Derivatives & Lipids;Glycerols;Inhibitors;Protein Kinase Inhibitors and Activators;Protein Kinase;Amines
Mol File:	123-78-4.mol

D-ERYTHRO-SPHINGOSINE Chemical Properties

Melting point	81-82 °C
Boiling point	440.8°C (rough estimate)
density	0.9758 (rough estimate)
refractive index	1.5000 (estimate)
storage temp.	−20°C
solubility	chloroform: 20 mg/mL, clear, colorless to very faintly yellow
form	Powder or Waxy Solid
color	White to cream
Merck	14,8747
Stability:	Stable. Incompatible with strong acids, strong bases, strong oxidizing agents.
CAS DataBase Reference	123-78-4

Safety Information

Safety Statements	22-24/25
WGK Germany	3
F	1-8-10
HS Code	29221985

MSDS Information

Provider	Language
ACROS	English
SigmaAldrich	English

D-ERYTHRO-SPHINGOSINE Usage And Synthesis

Chemical Properties	White Crystalline Solid
Uses	Selective inhibitor of protein kinase C activity and phorbol dibutyrate binding in vitro in human platelets; does not inhibit protein kinase A or myosin light chain kinase; inhibits calmodulin-dependent enzymes; natural isomer of sphingosine
Biological Activity	Inhibitor of protein kinase C and calmodulin-dependent enzymes, but may stimulate mast cells by activation of protein kinase C.
Purification Methods	D-Sphingosine is purified by recrystallisation from EtOAc, Et2O or pet ether (60-80o). It is insoluble in H2O but is soluble in Me2CO, EtOH and MeOH. It has IR bands at 1590 and 875 cm-1, and is characterised as the tribenzoate m 122-123o (from 95% EtOH). [Tipton Biochemical Preparations 9 127 1962.]

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