5-Bromoindole

$ 1.00 /1kg

Min. Order1kg
PurityAs customer's need
Cas No10075-50-0
Supply AbilityCARA27
Update time2019-07-06

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Chemical Properties

Product Name	5-Bromoindole
CAS No	10075-50-0
EC-No	233-208-7
Min. Order	1kg
Purity	As customer's need
Supply Ability	CARA27
Release date	2019/07/06

5-Bromoindole Basic information

Product Name:	5-Bromoindole
Synonyms:	5-BROMOBENZOTHOAZOLE;5-BROMOINDAN-1-ONE;5-BROMO INDOLE pure;1H-Indole, 5-bromo-;5-broMo-2H-indole;5-BroMoindole, 99% 5GR;5-BroMoindole (KSM-II);5-broMinatedindole
CAS:	10075-50-0
MF:	C8H6BrN
MW:	196.04
EINECS:	233-208-7
Product Categories:	IndolesOxindoles;Indole/indoline/oxindole;Indoles and derivatives;IndoleDerivative;Halides;Pyrroles & Indoles;Indole;Indoles;Organohalides;Simple Indoles;Pyrroles & Indoles;Halogenated Heterocycles;Heterocyclic Building Blocks;IndolesBuilding Blocks;Pharmaceutical Intermediates;Indole Derivatives;Heterocycle-Indole series;blocks;Bromides
Mol File:	10075-50-0.mol

5-Bromoindole Chemical Properties

Melting point	90-92 °C(lit.)
Boiling point	228.5°C (rough estimate)
density	1.5466 (rough estimate)
refractive index	1.6550 (estimate)
storage temp.	-20°C
solubility	126mg/l (calculated)
form	Powder or Chunks
color	White to light brown
BRN	112877
CAS DataBase Reference	10075-50-0(CAS DataBase Reference)
EPA Substance Registry System	1H-Indole, 5-bromo-(10075-50-0)

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36-24/25-37/39
WGK Germany	3
Hazard Note	Irritant
HS Code	29339990

MSDS Information

Provider	Language
5-Bromo-1H-indole	English
ACROS	English
SigmaAldrich	English
ALFA	English

5-Bromoindole Usage And Synthesis

Chemical Properties	white to light brown powder or chunks
Uses	A potential inhibitor of GSK-3
Purification Methods	Purify it by steam distillation from a faintly alkaline solution. Cool the aqueous distillate, collect the solid, dry it in a vacuum desiccator over P2O5 and recrystallise it from aqueous EtOH (35% EtOH) or pet ether/Et2O. UV in MeOH has at 279, 287 and 296nm (log 3.70, 3.69 and 3.53). The picrate has m 137-138o(dec) (from max Et2O/pet ether). [UV: Thesing et al. Chem Ber 95 2205 1962, UV and NMR: Lallemand & Bernath Bull Soc Chim Fr 4091 1970, Beilstein 20/7 V 36.]

5-Bromoindole Preparation Products And Raw materials

Preparation Products

1-METHYL-1H-INDOLE-5-BORONIC ACID 2,2-DIMETHYL PROPANE DIOL-1,3-CYCLIC ESTER-->C-(1H-INDOL-5-YL)-METHYLAMINE-->5-Indolylboronic acid-->5-Cyanoindole-->5-Acetylindole-->Indole-5-carboxaldehyde