Vitamin B2 (chemical formula: C17H20N4O6, formula 376.37), also known as riboflavin, is slightly soluble in water and is stable in heating in neutral or acidic solutions. It is a component of the flavin-based prosthetic group in the body (the yellow enzyme plays a hydrogen-promoting role in bio-oxidation). When it is lacking, it affects the biological oxidation of the body and causes metabolic disorder. The lesions are mostly manifested as inflammation of the mouth, eyes and external genital area, such as angular keratitis, cheilitis, glossitis, conjunctivitis and scrotal inflammation, so this product can be used for the prevention and treatment of the above diseases. The storage of vitamin B2 in the body is very limited, so it is provided daily by the diet. The two properties of vitamin B2 are the main causes of their loss: (1) can be destroyed by light; (2) heating in an alkaline solution can be destroyed.
Physicochemical properties;
Water-soluble vitamin, but slightly soluble in water, solubility at 127.5/100mL at 27.5 °C. It is soluble in sodium chloride solution, soluble in dilute sodium hydroxide solution, easily dissolved in alkaline solution, and stable in strong acid solution. Heat resistant and oxidation resistant. Irradiation and ultraviolet radiation cause irreversible decomposition.
Physiological function
It is mainly related to the active conjugated double bond present at the 1,5-position N on the isoxazine in the vitamin B2 molecule, and can be used as both a hydrogen donor and a hydrogen donor. In the human body, flavin adenine dinucleotide (FAD) and flavin mononucleotide (FMN) are involved in the redox reaction, which acts as a hydrogen donor and is a major auxiliary group of oxidoreductases in the body. Such as: succinate dehydrogenase, xanthine oxidase and NADH dehydrogenase.
The main biochemical reactions involved are respiratory chain energy production, amino acid and lipid oxidation, conversion of sulphate to uric acid, hydroxylation of aromatic compounds, synthesis of proteins and certain hormones, transport, storage and mobilization of iron, and participation in folic acid and pyridin. Metabolism of polyaldehydes and niacin.
1. Participate in biological oxidation and energy metabolism in the body, which is related to the metabolism of carbohydrates, proteins, nucleic acids and fats, which can improve the utilization of protein by the body, promote growth and development, and maintain the integrity of skin and cell membrane. It has the function of protecting the hair follicle mucosa and sebaceous glands.
2, involved in the growth and metabolism of cells, is an essential nutrient for the metabolism and repair of the body tissue, such as strengthening liver function, regulating the secretion of adrenaline.
3. Participation in the metabolism of vitamin B6 and niacin is a model for the coordination of B vitamins. FAD and FMN are used as prosthetic groups to participate in the conversion of tryptophan to niacin and the conversion of vitamin B6 to pyridoxal phosphate.
4. It is related to the absorption, storage and mobilization of the body iron.
5, also has antioxidant activity, may be related to the flavinase-glutathione reductase.
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