Oxytetracycline CAS 79-57-2 for Health Care
Oxytetracycline
Product Name: Oxytetracycline
Synonyms: 12,12a-hexahydroxy-6-methyl-1,11-dioxo-10;4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-,2-Naphthacenecarboxamide;5-hydroxy-tetracyclin;6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-,(4s-(4-alpha,4a-alpha,5-alpha,5a;6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-,[4s-(4alpha,4aalpha,5alpha,5a;6-beta,12a-alpha))--alph;adamycin;antibiotictm25
CAS: 79-57-2
MF: C22H24N2O9
MW: 460.43
EINECS: 201-212-8
Product Categories:
Mol File: 79-57-2.mol
| Product Name: |
Oxytetracycline
|
| Synonyms: |
4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide; 5-Hydroxytetracycline; Oxytetracycline Base; OTC Base; (2Z,4S,4aR,5S,5aR,6S,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,6,10,11,12a-pentahydroxy-6-methyl-4a,5a,6,12a-tetrahydrotetracene-1,3,12(2H,4H,5H)-trione; (4S,4aR,6S,12aS)-4-(dimethylamino)-3,5,6,10,12,12a-hexahydroxy-6-methyl-11-oxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide; 2-Naphthacenecarboxamide,4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo
|
| CAS RN.: |
79-57-2
|
| EINECS: |
201-212-8 |
| Molecular Weight: |
446.4504 |
| Molecular Formula: |
C22H26N2O8 |
| Density: |
1.645g/cm3 |
| Melting Point(℃): |
183℃ |
| Boiling Point(℃): |
817.08°C at 760 mmHg |
| Flash Point(℃): |
447.954°C |
Medical uses
Oxytetracycline, like other tetracyclines, is used to treat many infections, both common and rare (see Tetracycline antibiotics group). Its better absorption profile makes it preferable to tetracycline for moderately severe acne at a dosage of 250–500 mg four times a day for usually six to eight weeks at a time, but alternatives should be sought if no improvement occurs by three months. Avoid milk, iron, zinc or indigestion remedies while taking oxytetracycline. Take before food or on an empty stomach. Always follow your doctors' instructions and instruction leaflet.
It is sometimes used to treat spirochaetal infections, clostridial wound infection and anthrax in patients sensitive to penicillin. Oxytetracycline is used to treat infections of the respiratory and urinary tracts, skin, ear, eye and gonorrhoea, although its use for such purposes has declined in recent years due to large increases in bacterial resistance to this class of drugs. The drug is particularly useful when penicillins and/or macrolides cannot be used due to allergy. It may be used to treat Legionnaire's disease as a substitute for a macrolide or quinolone.
Oxytetracycline is especially valuable in treating nonspecific urethritis, Lyme disease, brucellosis, cholera, typhus, tularaemia. and infections caused by Chlamydia, Mycoplasma and Rickettsia. Doxycycline is now preferred to oxytetracycline for many of these indications because it has improved pharmacologic features.
The standard dose is 250–500 mg six-hourly by mouth. In particularly severe infections, this dose may be increased accordingly. Occasionally, oxytetracycline is given by intramuscular injection or topically in the form of creams, ophthalmic ointments or eye drops.
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