MOEXIPRIL HYDROCHLORIDE

$ 1.00 /1KG

career henan chemical co

VIP8Y

China

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MOEXIPRIL HYDROCHLORIDE Basic information

Product Name:	MOEXIPRIL HYDROCHLORIDE
Synonyms:	MOEXIPRIL HYDROCHLORIDE;(3S)-2-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3-phenyl-d5-propyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-3-isoquinolinecarboxylic Acid Hydrochloride;CI-925;Fempress;Perdix;RS-10085-197;SPM-925;Univasc
CAS:	82586-52-5
MF:	C27H35ClN2O7
MW:	535.03
EINECS:	1312995-182-4
Product Categories:	Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals;Aromatics;Inhibitors;API
Mol File:	82586-52-5.mol

MOEXIPRIL HYDROCHLORIDE Chemical Properties

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MSDS Information

MOEXIPRIL HYDROCHLORIDE Usage And Synthesis

Chemical Properties	Crystalline Solid
Uses	Angiotensin converting enzyme (ACE) inhibitor; dimethoxy analog of quinapril
Uses	Moexipril HCl is a potent orally active non-sulfhydryl angiotensin converting enzyme inhibitor (ACE) with IC50 of 0.041 μM, which is used for the treatment of hypertension and congestive heart failure
Biological Activity	Angiotensin-converting enzyme (ACE) inhibitor that is hydrolyzed in the liver to the active metabolite moexiprilat (IC 50 values are 2.1 and 2700 nM for moexiprilat and moexipril respectively). Antihypertensive; decreases mean blood pressure in the spontaneous hypertensive rat (SHR). Also blocks degradation of bradykinin into inactive metabolites.

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