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ChemicalBook Product Catalog S-(-)-Carbidopa

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S-(-)-Carbidopa

$ 1.00 /1KG

Min. Order1G
Purity98%
Cas No28860-95-9
Supply Ability100KG
Update time2019-07-06

career henan chemical co

career henan chemical co

7YR

China

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Chemical Properties

Product Name	S-(-)-Carbidopa
CAS No	28860-95-9
EC-No
Min. Order	1G
Purity	98%
Supply Ability	100KG
Release date	2019/07/06

AD68

S-(-)-Carbidopa Basic information

Product Name:	S-(-)-Carbidopa
Synonyms:	4-dihydroxy-alpha-methyl-alpha-hydrazino-(s)-benzenepropanoicaci;4-dihydroxy-alpha-methyl-alpha-hydrazino-l-hydrocinnamicaci;alpha-methyldopahydrazine;-Hydrazino-3,4-dihydroxy-methylbenzenep-ropanicacid;-Hydrazino-3,4-dihydroxy-methylhy-drocinnamicacid;hydrazino-alpha-methyldopa;l-alpha-methyldopahydrazine;mk486
CAS:	28860-95-9
MF:	C10H14N2O4
MW:	226.23
EINECS:	249-271-9
Product Categories:	L-Aromatic Amino Acid Decarboxylase;API;Lodosyn
Mol File:	28860-95-9.mol

S-(-)-Carbidopa Chemical Properties

Melting point	203-205° (dec); mp 208°
alpha	D -17.3° (methanol)
Boiling point	367.84°C (rough estimate)
density	1.2616 (rough estimate)
refractive index	1.5000 (estimate)
storage temp.	−20°C
form	powder
CAS DataBase Reference	28860-95-9(CAS DataBase Reference)

Safety Information

WGK Germany	3
RTECS	MW5298000

S-(-)-Carbidopa Usage And Synthesis

Chemical Properties	White Solid
Uses	(S)-(-)-Carbidopa is a peripheral decarboxylase inhibitor that is commonly used in combination with L-DOPA (D533751) for treatment of Parkinsonism. S(-)-Carbidopa ( has also been shown to prolong the elimination half-life of L-DOPA from blood plasma and skeletal muscle.
Uses	in combinaison with levodopa as antiparkinsonian;inhibits aromatic-L-amino-acid decarboxylase (DOPA Decarboxylase or DDC)
Definition	ChEBI: 3-(3,4-Dihydroxyphenyl)propanoic acid in which the hydrogens alpha- to the carboxyl group are substituted by hydrazinyl and methyl groups (S-configuration). Carbidopa is a dopa decarboxylase inhibitor, so prevents conversi n of levodopa to dopamine. It has no antiparkinson activity by itself, but is used (commonly as its hydrate) in the management of Parkinson's disease to reduce peripheral adverse effects of levodopa.
Biological Activity	Peripheral decarboxylase inhibitor, used in combination with levodopa for treatment of Parkinsonism.

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