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ChemicalBook Product Catalog API Circulatory system drugs Peripheral vasodilators Carvedilol

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Carvedilol

$ 1.00 /1KG

Min. Order1G
Purity98%
Cas No72956-09-3
Supply Ability100KG
Update time2019-07-06

career henan chemical co

career henan chemical co

7YR

China

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Chemical Properties

Product Name	Carvedilol
CAS No	72956-09-3
EC-No
Min. Order	1G
Purity	98%
Supply Ability	100KG
Release date	2019/07/06

AD68

Carvedilol Basic information

Product Name:	Carvedilol
Synonyms:	1-(9h-carbazol-4-yloxy)-3-((2-(2-methoxyphenoxy)ethyl)amino)-2-propano;CARVEDILOL;COREG;DIMITONE;DQ-2466;DILATREND;BM-14190;1-(9H-CARBAZOL-4-YLOXY)-3-[[2-(2-METHOXYPHENOXY)ETHYL]AMINO]-2-PROPANOL
CAS:	72956-09-3
MF:	C24H26N2O4
MW:	406.47
EINECS:	1308068-626-2
Product Categories:	Active Pharmaceutical Ingredients;Intermediates & Fine Chemicals;Pharmaceuticals;API's;Adrenoceptor;Aromatics;Heterocycles;API;LEVAQUIN;Cardiovascular Drugs
Mol File:	72956-09-3.mol

Carvedilol Chemical Properties

Melting point	113-117°C
storage temp.	Store at +4°C
solubility	DMSO: >20mg/mL
color	white to off-white
Merck	14,1873
CAS DataBase Reference	72956-09-3(CAS DataBase Reference)

Safety Information

Hazard Codes	N,Xn
Risk Statements	51/53-36/37/38-20/21/22
Safety Statements	61-36-26
RIDADR	UN 3077 9/PG 3
RTECS	UA8670000
HazardClass	IRRITANT
PackingGroup	III
Hazardous Substances Data	72956-09-3(Hazardous Substances Data)

Carvedilol Usage And Synthesis

Chemical Properties	Colourless Crystalline Solid
Uses	A nonselective -adrenergic blocker with a1-blocking activity. An antihypertensive used in the treatment of congestive heart failure.
Uses	An α1- and β-adrenergic receptor antagonist.
Uses	antibacterial
Uses	Carvedilol is a nonselective β-adrenergic blocker with α1-blocking activity. Carvedilol is an antihypertensive used in the treatment of congestive heart failure.
Uses	veterinary use
Uses	For the treatment of mild or moderate (NYHA class II or III) heart failure of ischemic or cardiomyopathic origin.
Definition	ChEBI: A member of the class of carbazoles that is an adrenergic antagonist with non-selective beta- and alpha-1 receptor blocking properties which helps in the management of congestive heart failure.
Biological Activity	Potent β -adrenoceptor and α 1 -adrenoceptor antagonist (K i values are 0.81, 0.96 and 2.2 nM for β 1 -, β 2 - and α 1 -adrenoceptors respectively) that displays antihypertensive and peripheral vasodilatory activity. Blocks cardiac inward-rectifier K + (K IR ) channels, voltage-dependent Ca 2+ channels and exhibits antioxidant properties at higher concentrations.

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