Benazepril hydrochloride

$ 1.00 /1KG

career henan chemical co

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China

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Benazepril hydrochloride Basic information

Product Name:	Benazepril hydrochloride
Synonyms:	1h-1-benzazepine-1-aceticacid,2,3,4,5-tetrahydro-3-((1-(ethoxycarbonyl)-3-phe;cgs14824a;monohydrochloride,(s-(r,r))-nylpropyl)amino)-2-oxo;BenazeprilHclC24H28N205.HC1;1H-1-Benzazepine-1-acetic acid, 3-(1S)-1-(ethoxycarbonyl)-3-phenylpropylamino-2,3,4,5-tetrahydro-2-oxo-, monohydrochloride, (3S)-;1H-1-Benzazepine-1-acetic acid, 3-[[1-(ethoxycarbonyl)-3-phenylpropyl]amino]-2,3,4,5-tetrahydro-2-oxo-, monohydrochloride, [S-(R,R)]-;CGS 14824A HCl;Lotensin
CAS:	86541-74-4
MF:	C24H29ClN2O5
MW:	460.95
EINECS:	1308068-626-2
Product Categories:	Intermediates & Fine Chemicals;Pharmaceuticals;Amines;Aromatics;Heterocycles;API;SONATA
Mol File:	86541-74-4.mol

Benazepril hydrochloride Chemical Properties

Melting point	188-190°C
alpha	D -141.0° (c = 0.9 in ethanol)
storage temp.	Desiccate at +4°C
solubility	DMSO: ~34 mg/mL, soluble
form	solid
color	white
Merck	14,1031
InChIKey	VPSRQEHTHIMDQM-FKLPMGAJSA-N
CAS DataBase Reference	86541-74-4(CAS DataBase Reference)

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Benazepril hydrochloride Usage And Synthesis

Chemical Properties	Crystalline Solid
Uses	sedative, hypnotic
Uses	Used as an antihypertensive; angiotensin converting enzyme inhibitor.
Definition	ChEBI: A hydrochloride salt resulting from the reaction of benazepril with 1 mol eq. of hydrogen chloride. It is used as a prodrug for angiotensin-converting enzyme inhibitor benazeprilat in the treatment of hypertension and heart failure.
Biological Activity	Non-peptide angiotensin-converting enzyme (ACE) inhibitor. Reduces blood pressure and myocardial hypertrophy in spontaneous hypertensive rats.

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