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ChemicalBook Product Catalog API Antibiotics Other antibiotic Drugs Nigericin sodium salt

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Nigericin sodium salt

$ 1.00 /1KG

Min. Order1G
Purity98%
Cas No28643-80-3
Supply Ability100KG
Update time2019-07-06

career henan chemical co

career henan chemical co

7YR

China

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Chemical Properties

Product Name	Nigericin sodium salt
CAS No	28643-80-3
EC-No
Min. Order	1G
Purity	98%
Supply Ability	100KG
Release date	2019/07/06

AD68

Nigericin sodium salt Basic information

Product Name:	Nigericin sodium salt
Synonyms:	Polyetherin A, Azalomycin M, Helixin C, Antibiotic K178, Antibiotic X-464;Antibiotic K178, Antibiotic X464, Azalomycin M, Helexin C, Polyetherin A;Sodium (2R)-2-[(3S,6R)-6-[[(2S,4R,5R,7R,9R,10R)-2-[(5S)-5-[(2R,3S,5R)-5-[(2S,3S,5R,6R)-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyloxan-2-yl]-3-methyloxolan-2-yl]-5-methyloxolan-2-yl]-9-methoxy-2,4,10-trimethyl-1,6-dioxaspiro[4.5]decan-7-yl]methyl]-3-methyloxan-2-yl]propanoate;Nigericin sodium salt;Nigericin, monosodium salt;Nsc292567;Nigericin sodium salt,Antibiotic K178, Antibiotic X464, Azalomycin M, Helexin C, Polyetherin A;Nigericin sodiuM sa
CAS:	28643-80-3
MF:	C40H67O11Na
MW:	746.94
EINECS:
Product Categories:	API
Mol File:	28643-80-3.mol

Nigericin sodium salt Chemical Properties

storage temp.	2-8°C
solubility	Soluble in chloroform, methanol or ethanol
Merck	13,6569
InChIKey	MOYOTUKECQMGHE-NTQCAYBPSA-M

Safety Information

Hazard Codes	T
Risk Statements	25-36/37/38
Safety Statements	26-36/37/39-45
RIDADR	UN 3462 6.1/PG 3
RTECS	QT6840000
HazardClass	6.1
HS Code	29419090

MSDS Information

Nigericin sodium salt Usage And Synthesis

Chemical Properties	White powder
Uses	Nigericin sodium is the atypical salt of nigericin. Since nigericin is an ionophore, its very high affinity for monovalent cations such as Na+ and K+ means that formation of a salt is a facile possess occurring during purification under any but highly acidic conditions. Typically, the salts of polyether ionophores like the free acid, are readily extracted into organic solvents. The sodium ion is stabilised within a polar pocket of the structure, effectively making the salt and free acid different chemical moieties with the potential for differing pharmacology, a fact not readily appreciated in the literature.
Uses	Nigericin sodium is a salt of the atypical polyether antibiotic, nigericin. Since nigericin is an ionophore, its very high affinity for monovalent cations such as Na+ and K+ means that formation of a salt is a facile possess occurring during purification under any but highly acidic conditions. Typically, the salts of polyether ionophores like the free acid, are readily extracted into organic solvents. The sodium ion is stabilised within a polar pocket of the structure, effectively making the salt and free acid different chemical moieties with the potential for differing pharmacology, a fact not readily appreciated in the literature.

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