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Zidovudine

$ 1.00 /1KG

Min. Order1G
Purity98%
Cas No30516-87-1
Supply Ability100KG
Update time2019-07-06

career henan chemical co

career henan chemical co

6YR

China

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Chemical Properties

Product Name	Zidovudine
CAS No	30516-87-1
EC-No
Min. Order	1G
Purity	98%
Supply Ability	100KG
Release date	2019/07/06

AD68

Zidovudine Basic information

Product Name:	Zidovudine
Synonyms:	1-(4-azido-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione;1-(4-azido-5-methylol-tetrahydrofuran-2-yl)-5-methyl-pyrimidine-2,4-quinone;1-[4-azido-5-(hydroxymethyl)-2-tetrahydrofuranyl]-5-methylpyrimidine-2,4-dione;1-[4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-pyrimidine-2,4-dione;1-[4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione;1-[4-azido-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-methylpyrimidine-2,4(1H,3H)-dione;1-[4-azido-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-methyl-pyrimidine-2,4-dione;3'-Deoxy-3'-azidothymi
CAS:	30516-87-1
MF:	C10H13N5O5
MW:	283.24
EINECS:	1308068-626-2
Product Categories:	Amino Acids;Miscellaneous Natural Products;Antivirals for Research and Experimental Use;Biochemistry;Chemical Reagents for Pharmacology Research;Nucleosides and their analogs;Nucleosides, Nucleotides & Related Reagents;Bases & Related Reagents;Intermediates & Fine Chemicals;Nucleotides;Pharmaceuticals;API's;Antiviral;HIV/AIDS/Related Products;API;VIOCIN
Mol File:	30516-87-1.mol

Zidovudine Chemical Properties

Melting point	113-115 °C(lit.)
alpha	D25 +99° (c = 0.5 in water)
Boiling point	410.43°C (rough estimate)
density	1.3382 (rough estimate)
refractive index	47 ° (C=1, H2O)
Fp	9℃
storage temp.	−20°C
solubility	H₂O: 50 mg/mL
form	Powder
color	White to Off-white
Water Solubility	1-5 g/100 mL at 17 ºC
Sensitive	Light Sensitive & Hygroscopic
Merck	14,10123
InChIKey	HBOMLICNUCNMMY-BWZBUEFSSA-N
CAS DataBase Reference	30516-87-1(CAS DataBase Reference)
EPA Substance Registry System	Thymidine, 3'-azido-3'-deoxy- (30516-87-1)

Safety Information

Hazard Codes	Xn
Risk Statements	40-36/37/38-20/21/22
Safety Statements	36/37/39-45-36-26
RIDADR	UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany	3
RTECS	XP2072000
F	10
Hazard Note	Harmful
HS Code	29349990
Hazardous Substances Data	30516-87-1(Hazardous Substances Data)
Toxicity	LD50 in male, female mice, male, female rats (mg/kg): 3568, 3062, 3084, 3683 orally; >750 i.v. (all species) (Ayers)

Zidovudine Usage And Synthesis

Chemical Properties	Off White Crystalline Powder
Uses	antibacterial
Uses	A potent and selective inhibitor of HIV-1 replication
Definition	ChEBI: A pyrimidine 2',3'-dideoxyribonucleoside compound having a 3'-azido substituent and thymine as the nucleobase.
General Description	Slightly off-white odorless powdery solid.
Air & Water Reactions	Dust may form an explosive mixture in air. Water soluble. Hydrolysis occurs in strongly basic solutions .
Reactivity Profile	Zidovudine is a azido compound. Azo, diazo, azido compounds can detonate. This applies in particular to organic azides that have been sensitized by the addition of metal salts or strong acids. Toxic gases are formed by mixing materials of this class with acids, aldehydes, amides, carbamates, cyanides, inorganic fluorides, halogenated organics, isocyanates, ketones, metals, nitrides, peroxides, phenols, epoxides, acyl halides, and strong oxidizing or reducing agents. Flammable gases are formed by mixing materials in this group with alkali metals. Explosive combination can occur with strong oxidizing agents, metal salts, peroxides, and sulfides.
Fire Hazard	Flash point data for Zidovudine are not available; however, Zidovudine is probably combustible.

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